2006
DOI: 10.1157/13083251
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Influencia de los antiinflamatorios no esteroideos en la hemorragia digestiva por úlceras o erosiones gastroduodenales en pacientes con cirrosis hepática

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Cited by 20 publications
(7 citation statements)
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“… 969 They are responsible for 10% of cases of drug-induced hepatitis 970 and are reported to cause hepatotoxicity. 957 , 971 Furthermore, NSAIDs can cause side effects such as nephrotoxicity, 972 gastric ulcers or bleeding, 973 , 974 and decompensation 964 in patients with liver cirrhosis; therefore, their use must be avoided as much as possible. In patients with bone metastasis, COX-2 inhibitors (rofecoxib, celecoxib, valdecoxib) are used to alleviate pain by inhibiting prostaglandin synthesis.…”
Section: Drug Treatment For Cancer Pain In Hccmentioning
confidence: 99%
“… 969 They are responsible for 10% of cases of drug-induced hepatitis 970 and are reported to cause hepatotoxicity. 957 , 971 Furthermore, NSAIDs can cause side effects such as nephrotoxicity, 972 gastric ulcers or bleeding, 973 , 974 and decompensation 964 in patients with liver cirrhosis; therefore, their use must be avoided as much as possible. In patients with bone metastasis, COX-2 inhibitors (rofecoxib, celecoxib, valdecoxib) are used to alleviate pain by inhibiting prostaglandin synthesis.…”
Section: Drug Treatment For Cancer Pain In Hccmentioning
confidence: 99%
“…Indeed, roughly 10% of total drug-induced hepatotoxicity cases are related to NSAIDs,709 and NSAID-induced liver injury is well documented 695,710. Moreover, NSAIDs can cause adverse effects, including nephrotoxicity,711 gastric ulcer, hemorrhage,59,60,712,713 and decompensation of liver function 703…”
Section: Drug Treatment For Cancer Pain In Hccmentioning
confidence: 99%
“…Indeed, roughly 10% of total drug-induced hepatotoxicity cases are related to NSAIDs (709), and NSAID-induced liver injury is well documented (695710). Moreover, NSAIDs can cause adverse effects, including nephrotoxicity (711), gastriculcer, hemorrhage (5960712713), and decompensation of liver function (703).…”
Section: Drug Treatment For Cancer Pain In Hccmentioning
confidence: 99%