Influencia de la ganancia de peso durante el primer año del trasplante renal en la sobrevida de injertos y pacientes

Vega, Jorge; E, Juan Pablo Huidobro; Barra, Sofía De La; Haro, D.

doi:10.4067/s0034-98872015000800001

Cited by 8 publications

(6 citation statements)

References 45 publications

(64 reference statements)

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“…Weight gain within the first year of greater than 5% is associated with a threefold increase in kidney graft loss (Ducloux, Kazory, Simula-Faivre, & Chalopin, 2005). Furthermore, weight gain of greater than 15% is associated with increased non-kidney related mortality within 10 years (Vega, Huidobro, De La Barra, & Haro, 2015). Therefore, interventions should target weight gain as a potentially modifiable risk factor for new KTRs (Henggeler et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Usability and experience testing to refine an online intervention to prevent weight gain in new kidney transplant recipients

Castle

Greenwood

Chilcot

et al. 2020

British J Health Psychol

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Objectives. Weight gain in the first year following kidney transplantation increases the risk of adverse health outcomes. Currently, there is no recognized intervention available to prevent weight gain after kidney transplantation. An online kidney transplant-specific resource, entitled Exercise in Renal Transplant Online (ExeRTiOn), has been co-created by a multi-professional team, including patients, to assist with weight prevention. This study aimed to evaluate patient and health care professional usability and experience of the ExeRTiOn online resource. Design. Qualitative study utilizing 'Think-Aloud' and semi-structured interviews. Methods. Participants (n = 17) were purposively sampled to include new kidney transplant recipients (n = 11) and transplant health care professionals (n = 6). Kidney transplant recipient participants were from a spread of physical activity levels based on scores from the General Practice Physical Activity Questionnaire (GPPAQ). 'Think-Aloud' interviews assessed the usability of ExeRTiOn. Semi-structured interviews explored participants' experience of ExeRTiOn, weight gain, and physical activity. The data set were analysed thematically. Participant characteristics, including login data and self-reported body weight, were collected. Results. Data analyses identified valued intervention content and usability aspects which were summarized by two themes. The first theme 'You need to know how to manage yourself' included subthemes: (1) the resource filled a guidance gap, (2) expert patient content resonated, and (3) the importance of goal setting and monitoring progress. The second theme 'room for improvement' included subthemes: (2) web support and (2) content and operational change suggestions.

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Section: Introductionmentioning

confidence: 99%

Usability and experience testing to refine an online intervention to prevent weight gain in new kidney transplant recipients

Castle

Greenwood

Chilcot

et al. 2020

British J Health Psychol

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“…The nutritional classifications "overweight" or "obesity" are classified as comorbidities and have a strong association disease development, potentially reducing the survival of the renal graft after KT (32). Kidney transplantation patients may be at greater risk of obesity, as body mass increases an average of 10% in the first year (43).…”

Section: Introductionmentioning

confidence: 99%

Effects of Combined Resistance Plus Aerobic Training on Body Composition, Muscle Strength, Aerobic Capacity, and Renal Function in Kidney Transplantation Subjects

Lima

Campos

Neto

et al. 2019

Journal of Strength and Conditioning Research

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Effects of combined resistance plus aerobic training on body composition, muscle strength, aerobic capacity, and renal function in kidney transplantation subjects. J Strength Cond Res 35(11): 3243-3250, 2021-Immunosuppression and a sedentary lifestyle may exacerbate complications such as early graft dysfunction and muscle loss, and reduce patient survival after kidney transplantation (KT). Therefore, the purpose of this study was to evaluate changes in body composition (BC), muscular strength, aerobic, and renal function in KT subjects submitted to combined resistance plus aerobic training. Twelve KT subjects were randomly assigned into groups: (G1) 12 weeks of combined training (3 males and 4 females, 54 6 3 years); or (G2) nonexercise control (5 females, 43 6 18 years). The subjects were evaluated for BC (dual-energy X-ray absorptiometry), estimated V Ȯ2 peak, right-hand maximal grip strength (RHMGS) and left-hand maximal grip strength (LHMGS), and renal function. Post-training revealed that G1 reduced body fat percentage (p 5 0.046), uric acid (D 5 20.87; p 5 0.023), urea (D 5 29.43; p 5 0.032), and creatinine (D 5 20.15; p 5 0.045), increased fat-free mass, estimated V Ȯ2 peak, RHMGS, LHMGS (p , 0.05), and estimated glomerular filtration rate (eGFR) (D 5 11.64; p 5 0.017). G2 increased urea (D 5 8.20; p 5 0.017), creatinine (D 5 0.37; p 5 0.028), and decreased eGFR (D 5 216.10; p 5 0.038). After 12 weeks, urea (D 5 24.94; p 5 0.013), uric acid (D 5 1.64; p 5 0.044), and creatinine (D 5 0.9; p 5 0.011) were lower, whereas eGFR (D 5 36.51; p 5 0.009) was higher in G1. These data indicate that combined training instigates positive changes in BC, muscular strength, aerobic capacity, and renal function after KT.

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“…Studies that include participants with an older transplant vintage were excluded, which may have precluded additional insight into this research area. However, as weight gain within the first year is associated with adverse clinical outcomes [6,72], the authors felt it was important to investigate the first year post kidney transplantation.…”

Section: Strengths and Limitationsmentioning

confidence: 99%

“…Weight gain within the first year of receiving a kidney is a critical health issue [5]. KTRs who gain more than 15% of their body weight within the first year of transplant surgery are at an increased risk of death with a functioning kidney [6]. The factors underlying post kidney transplant weight gain include reduced physical function [7] and physical activity (PA) [8], increased appetite [9], steroid medication use [10], and the lifting of dietary restrictions [11].…”

Section: Introductionmentioning

confidence: 99%

Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

Castle

McBride

Greenwood

et al. 2021

Kidney and Dialysis

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Weight gain within the first year of kidney transplantation is associated with adverse outcomes. This narrative systematic review and meta-analysis examines the effect of exercise, physical activity, dietary, and/or combined interventions on body weight and body mass index (BMI) within the first year of kidney transplantation. Seven databases were searched from January 1985 to April 2021 (Prospero ID: CRD42019140865), using a ‘Population, Intervention, Controls, Outcome’ (PICO) framework. The risk-of-bias was assessed by two reviewers. A random-effects meta-analysis was conducted on randomized controlled trials (RCTs) that included post-intervention body weight or BMI values. Of the 1197 articles screened, sixteen met the search criteria. Ten were RCTs, and six were quasi-experimental studies, including a total of 1821 new kidney transplant recipients. The sample sizes ranged from 8 to 452. Interventions (duration and type) were variable. Random-effects meta-analysis revealed no significant difference in post-intervention body weight (−2.5 kg, 95% CI −5.22 to 0.22) or BMI (−0.4 kg/m2, 95% CI −1.33 to 0.54). Despite methodological variance, statistical heterogeneity was not significant. Sensitivity analysis suggests combined interventions warrant further investigation. Five RCTs were classified as ‘high-risk’, one as ‘some-concerns’, and four as ‘low-risk’ for bias. We did not find evidence that dietary, exercise, or combined interventions led to significant changes in body weight or BMI post kidney transplantation. The number and quality of intervention studies are low. Higher quality RCTs are needed to evaluate the immediate and longer-term effects of combined interventions on body weight in new kidney transplant recipients.

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Influencia de la ganancia de peso durante el primer año del trasplante renal en la sobrevida de injertos y pacientes

Cited by 8 publications

References 45 publications

Usability and experience testing to refine an online intervention to prevent weight gain in new kidney transplant recipients

Usability and experience testing to refine an online intervention to prevent weight gain in new kidney transplant recipients

Effects of Combined Resistance Plus Aerobic Training on Body Composition, Muscle Strength, Aerobic Capacity, and Renal Function in Kidney Transplantation Subjects

Do Exercise, Physical Activity, Dietetic, or Combined Interventions Improve Body Weight in New Kidney Transplant Recipients? A Narrative Systematic Review and Meta-Analysis

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