Influência Das Condições De Reação Na Produção De Nanopartículas No Grau De Encapsulamento Do Cardanol

Cardanol, principal constituent of the technical cashew nut shell liquid, has applications as antioxidant and antibacterial, and these properties may be enhanced through encapsulation. In the present study, we isolated and purified cardanol, and nanoparticles (NPs) were produced by polyelectrolyte complexation using polysaccharide systems with chitosan, sodium alginate, and non-toxic Arabic gum, because they are biocompatible, biodegradable, and stable. We characterized the NPs for morphological, physicochemical, and antioxidant activity. The micrographs obtained revealed spherical and nanometric morphology, with 70% of the distribution ranging from 34 to 300 nm, presenting a bimodal distribution. The study of the spectra in the infrared region suggested the existence of physicochemical interactions and cross-links between the biopolymers involved in the encapsulated NPs. Furthermore, the NPs showed better antioxidant potential when compared to pure cardanol. Thus, the encapsulation of cardanol may be an effective method to maintain its properties, promote better protection of the active ingredient, minimize side effects, and can target its activities in specific locations, by inhibiting free radicals in various sectors such as pharmaceutical, nutraceutical, and biomedical.

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Chitosan-Based Nanoparticles for Cardanol-Sustained Delivery System

Valério

Silva

Paiva

et al. 2022

Polymers

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Influência Das Condições De Reação Na Produção De Nanopartículas No Grau De Encapsulamento Do Cardanol

Abstract: Influência das condições de reação na produção de nanopartículas no grau de encapsulamento do cardanol Influence of reaction conditions on the production of nanoparticles on the degree of encapsulation of cardanol

Cited by 1 publication

References 11 publications

Chitosan-Based Nanoparticles for Cardanol-Sustained Delivery System

Chitosan-Based Nanoparticles for Cardanol-Sustained Delivery System

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