Influences on childhood depressive symptoms: The effects of trauma and distress tolerance across age and sex groups

Rette, Danielle; Arnold, Molly; McDonald, Erin; Hoptman, Matthew J.; Collins, Katherine A.; Iosifescu, Dan V.

doi:10.1016/j.jad.2021.01.064

Cited by 5 publications

(4 citation statements)

References 14 publications

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“…Previous literature suggests that cancer, as a traumatic experience, is associated with the risk of depression in childhood cancer survivors 39 . After experiencing childhood trauma, boys reported being more avoidant and disengaged, and hard to stop worrying, anhedonia, and concentration problems than girls 8,40 . This manifestation may be more pronounced in boys than girls with moderate depression.…”

Section: Discussionmentioning

confidence: 86%

“…39 After experiencing childhood trauma, boys reported being more avoidant and disengaged, and hard to stop worrying, anhedonia, and concentration problems than girls. 8,40 This manifestation may be more pronounced in boys than girls with moderate depression.…”

Section: Discussionmentioning

confidence: 99%

“…The recent literature suggests that sex and age are significant predictors of child depression severity, with boys reporting more depression than girls during childhood (age group 7-10 years) and girls reporting more depression at the onset of puberty and through adolescence (age group 11-17 years). 8 Other studies also suggest that sex and age are risk factors for depression in patients receiving chemotherapy. 9 Various factors associated with cancer and its treatment may influence the development of depression, including cancer type, stage and prognosis.…”

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confidence: 99%

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Sex differences in depression for childhood cancer survivors

Wang

et al. 2022

Psycho-Oncology

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Objective This study examines the differential association between sex and depression, and the possible mediating pathways. Methods We analysed survey data from 296 (age 7–17.1 years) cancer survivors from three centres affiliated with Beijing Children's Hospital. Linear regression analysis was used to assess the association between sex and depression. Quantile regression analysis was used to estimate the regression coefficients (β) and 95% confidence intervals for sex in depression at different quantiles. Mediation analysis with multiple mediators was used to explore the effects of sex on depression. Results Using linear regression, we found that the age ranged from 8.7 to 10.4 years and the regression coefficient of sex on depression was significant (β = −2.75, p = 0.03). Quantile regression results showed a significant negative association between sex and depression in the 0.30–0.75 quantiles. Mediation analysis revealed that boys were 1.545 times more depressed than girls, with family resilience, self‐perceived burden, and behavioural problems explaining approximately 16.79%, 21.57%, and 43.94% of the sex difference, respectively. The combined effect of family functioning, resilience, social support, self‐perceived burden, and behavioural problems might explain the 89.17% sex difference. Conclusion Clinicians should consider sex effects when assessing depression in childhood cancer survivors and target sex‐specific interventions for further treatment.

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Section: Discussionmentioning

confidence: 86%

Section: Discussionmentioning

confidence: 99%

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confidence: 99%

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Sex differences in depression for childhood cancer survivors

Wang

et al. 2022

Psycho-Oncology

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“…In these analyses, depression severity was included as the dependent variable; CTI and five subtypes of childhood trauma were regarded as the independent variables. Age and gender were included as covariates, as prior research has revealed their significant effects on both depression and trauma [ 12 , 54 ].…”

Section: Methodsmentioning

confidence: 99%

Self-concept mediates the relationships between childhood traumatic experiences and adolescent depression in both clinical and community samples

Hu,

Yang,

et al. 2024

BMC Psychiatry

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Background Childhood trauma is a pivotal risk factor for adolescent depression. While the association between childhood trauma and depression is well-established, the mediating role of self-concept has not been acknowledged. Specifically, limited attention has been paid to how childhood maltreatment impacts adolescent depression through physical and social self-concept, both in clinical and community samples. This study aims to investigate how distinct and cumulative childhood trauma affects adolescent depression, as well as the potential mediating role of self-concept in their relationships. Methods We recruited 227 depressed adolescents (dataset 1, 45 males, age = 15.34 ± 1.96) and 574 community adolescents (dataset 2, 107 males, age = 16.79 ± 0.65). Each participant was assessed on five subtypes of childhood trauma severity, cumulative trauma index, physical and social self-concept, and depression. Mediation models were tested separately in the clinical and community samples. Results Clinically depressed adolescents experienced a higher level of trauma severity, a greater number of trauma subtypes, and had lower levels of physical and social self-concept compared to community adolescents. Analyses on childhood trauma severity and cumulative trauma index jointly indicated that physical and social self-concept played mediation roles in the relationships between childhood trauma experiences and depression. Moreover, the mediating effects of self-concept were stronger in depressed adolescents when compared to community samples. Conclusions Our findings suggest that physical and social self-concept play mediating roles in the pathway linking childhood trauma and adolescent depression, particularly in clinically depressed individuals.

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The relationship between distress tolerance and behavioral activation on anxiety and depression symptomatology in autistic youth: Leveraging self and caregiver perspectives

Schwartzman,

Antezana,

Conner

2024

Autism Research

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Anxiety and depression are prevalent among autistic adolescents and may be difficult to accurately diagnose and treat given various factors (e.g., diagnostic overshadowing, heterogeneity). Therefore, efforts to examine transdiagnostic factors (i.e., distress tolerance, behavioral activation) may afford more parsimonious means for assessment and treatment. To our knowledge, there has been little research on distress tolerance, behavioral activation, and depressive and anxiety symptoms in autistic adolescents to guide diagnostic practices and treatment planning. In the current study, we examined the interrelationships between these transdiagnostic factors and depressive and anxiety symptoms using ratings from 100 verbally fluent autistic adolescents without intellectual disability (Mage = 13.70, SDage = 2.23, Range: 11:00–17:11 years) and 100 of their caregivers. Many adolescents reported male sex assigned at birth (61%), cisgender (87%), not Hispanic/Latinx (90%), and White (80%) identities. A series of correlational analyses were employed to examine associations between these constructs from youth and caregiver perspectives, and multiple linear regression analyses were conducted to explore the mediating roles of distress tolerance and behavioral activation. Preliminary results show that low distress tolerance and behavioral activation were associated with more severe internalizing symptoms per self‐ and caregiver‐report. Some differences by rater emerged, which highlight the importance of multi‐informant ratings in autism. Results from mediation analyses may show that behavioral activation may be more salient to assessments and treatment planning for depression than distress tolerance, while distress tolerance may be important for both anxiety and depression; however, findings are preliminary given the cross‐sectional nature of the data. Findings suggest that these transdiagnostic concepts may be important to individualizing treatment approaches, including the timing of certain approaches, for anxiety and/or depression in autistic adolescents.

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Influences on childhood depressive symptoms: The effects of trauma and distress tolerance across age and sex groups

Cited by 5 publications

References 14 publications

Sex differences in depression for childhood cancer survivors

Sex differences in depression for childhood cancer survivors

Self-concept mediates the relationships between childhood traumatic experiences and adolescent depression in both clinical and community samples

The relationship between distress tolerance and behavioral activation on anxiety and depression symptomatology in autistic youth: Leveraging self and caregiver perspectives

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