Influences of Central Bouquet Alterations on the Visual Outcome in Eyes Receiving Epiretinal Membrane Surgery

Abstract

Background: Previous studies have shown that epiretinal membranes (ERMs) may be associated with abnormal outer retinal anatomy. However, long-term morphological and functional results of pars plana vitrectomy (PPV) with ERM and internal limiting membrane (ILM) peeling in eyes with central bouquet (CB) alterations have not yet been investigated. Methods: In a retrospective, consecutive study all patients underwent best corrected visual acuity (BCVA) testing and spectral domain optical coherence tomography (SD-OCT) before and after a mean of 20 months (range 3–70 months) postoperatively. CB abnormalities and ERMs were classified according to Govetto’s staging systems. Results: Of the 67 eyes, 22 (34%) showed CB abnormalities at baseline. The mean BCVA increased from 0.42 at baseline to 0.20 LogMAR at final follow-up (p < 0.001). Neither ERM stage (p = 0.06) nor CB stage (p = 0.939) at baseline were significant predictors of vision improvement following surgery. Conclusions: Our results show that baseline BCVA, but not classification of CB changes and ERM at baseline, seems to be a useful predictor for functional outcomes following PPV with ERM and ILM peeling in the long-term.

Analysis of the Peripapillary and Macular Regions Using OCT Angiography in Patients with Schizophrenia and Bipolar Disorder

“…Therefore, researchers have suggested that retinal changes can serve as a marker of progressive brain tissue loss [ 8 , 9 , 10 ]. This has prompted the use of a non-invasive retinal imaging technology, i.e., optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) [ 11 , 12 , 13 , 14 , 15 ]. They have been used in a wide spectrum in ophthalmology, to assess the thickness, volume, and structure of different layers of the retina [ 16 , 17 , 18 , 19 , 20 ].…”

Association of Microvasculature and Macular Sensitivity in Idiopathic Macular Epiretinal Membrane: Using OCT Angiography and Microperimetry

“…Visual prognostic factors of ERM surgery are varied and inconsistent in previous study with duration of symptoms, central bouquet (CB) alteration staging, and existence of pseudoholes having been reported as possible predictive factors ( 31 , 32 ). In long-term prognosis, BCVA at baseline, but not classification of CB, appeared to be a strong predictor for BCVA improvement following surgery ( 26 ). The CFT has been identified as a significant predictor in some study ( 31 ), but not others ( 33 , 34 ).…”

“…Poor quality images with segmentation errors, motion artifacts, or low signal strength index (<50) were excluded. iERM was defined with OCTA B-scans as a thin hyperreflective band anterior to the ILM with focal areas of macular attachments or globally adherent to the retinal surface ( 26 ). A staging system reported by Govetto et al was used to classify iERM ( 27 ).…”

Relationship of Vessel Density to Vessel Length Density in Patients with Treated Fabry Disease

“…These are among the most common parameters used for the detection of differences in the retinal vasculature using OCTA, although it has been recognized by some authors, that these parameters only provide partial information about the actual state of the retinal vasculature [ 26 ]. Previous studies have addressed this issue, but to date, there is no comprehensive single OCTA parameter replacing VD and VLD, which are still the most commonly used parameters in the scientific literature [ 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ].…”