Influence Spironalactone on blood glucose, heart arrhythmias and arterial blood pressure

Abstract

Spironolactone is a diuretic and is often used in the treatment of hypertension. This medicine is very good when it comes to lowering the blood pressure, and this is also a drug of choice when it comes to the stage of hypertensive urgencies and emergencies. It can be administered intravenously, and the effects reach a maximum within 30 minutes. Due to the fact that this medicine can causes hifher level of potassium ions it can a blood glucose and arrhythmias. A prospective random study was carried out in Hemodyalisis center of Public Health Institution Center “Zivinice’’, where we analyzed 120 patients which were suffering from hypertension heart disease, and diabetes. We included all 120 patient whom suffering from hypertension and diabetes. Clinical and laboratory data of patients were collected during period from February to August 2022. Looking at all the three groups of patients, it can be noticed that the maximum value of arterial blood pressure upon arrival at the Hemodyalisis ceneter had patients suffering from hypertension and diabetes, where the average value of arterial blood pressure was 173/113 mmHg. According to analysis for all three observed groups of patients, after treatment with spironolactone there is no statistical significance in the incidence of arrhythmias between the groups where. Looking at the summary for all three groups of patients, the average value increase of blood glucose after treatment with spironolactone is 0.9 mmol/l. Spironolactone is safe for the treatment of hypertension in diabetic patients.