Influence of visible light on cutaneous hyperchromias: Clinical efficacy of broad‐spectrum sunscreens

Martini, A. P.; Campos, Patrícia Maria Berardo Gonçalves Maia

doi:10.1111/phpp.12377

Cited by 32 publications

(33 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The pores visible on the image were marked and interpreted as a percentage according to the whole image. Then, the classification of large of fine pores was done according to the obtained percentage in the analyzed image (Courage and Khazaka electronic GmbH, 2014; Martini and Maia Campos, 2018).…”

Section: Methodsmentioning

confidence: 99%

Use of Advanced Imaging Techniques for the Characterization of Oily Skin

2019

Self Cite

View full text Add to dashboard Cite

Excessively oily skin leads to clinical signs that cause discomfort to patients, such as excessive shine, enlarged pores, acne, and an imbalance of the hydrolipidic layer. In this context, a constant demand for the research and development of products that prevent these features, has been noted in the field of cosmetics and dermatology. Thus, the objective of this study is to evaluate the cutaneous characteristics of oily skin due an excessive production of sebum through biophysical and skin imaging techniques. 19 participants with different skin types were selected and the following parameters were evaluated: pore count, determination of the number of sebaceous glands and amount of sebum in infundibulum, determination of cutaneous microrelief, count of comedones, evaluation of epidermis thickness, characterization of the cellular, and comedone size and its characteristics. These evaluations were done through biophysical and skin imaging techniques. The obtained results showed that different regions of the face presented different characteristics related to oiliness, quantity, and the appearance of pores and comedones. The malar region had a lower epidermis thickness and a larger number of large pores. Moreover, in this region excessive sebum production, which can be related to pores, not comedones, was noted. The nose region presented higher sebum content in the infundibulum and lower active sebaceous glands, showing a higher activity of sebaceous production in this region. The chin region presented a positive correlation between the sebum content, roughness parameter and the number of pores and comedones. As different skin properties are related and influence the appearance of undesirable clinical signs, we identified the need for a multifactorial approach for the effective treatment of oily skin. The rational development of multifunctional cosmetic products that promote the control of oily skin, that regulate the keratinization process, improve the microrelief and leads to a better epidermis and dermis structure, will not only improve oily skin conditions but will also allow for the reduction or disappearance of clinical signs that result from excessive oiliness, all of which causes concern and results in a relentless search for cosmetic and dermatological products that address the unaesthetic nature of these conditions.

show abstract

Section: Methodsmentioning

confidence: 99%

Use of Advanced Imaging Techniques for the Characterization of Oily Skin

2019

Self Cite

View full text Add to dashboard Cite

show abstract

“…The calculation of the percentage of transmittance reduction (%) in the VL range, used in our previous publications,17,21 is based on the following equation:…”

Section: Methodsmentioning

confidence: 99%

“…The availability of sunscreens containing pigments, particularly iron oxide, has revolutionized the treatment and prevention of pigmentary disorders, precisely by providing protection (essentially by reflection) within the long UVA and high energy VL range 1. The use of colored sunscreens (UVR+VIS) showed to be more efficient in avoiding melasma recurrence compared to equivalent UV protection sunscreens, but without protection against the VL 16,17. When associated with bleaching therapy in patients with melasma, sunscreens with VL protection enhanced the response, with a greater reduction of epidermal melanin content and number of mast cells in the dermis 18…”

Section: Introductionmentioning

confidence: 99%

<p>A novel method for evaluating sun visible light protection factor and pigmentation protection factor of sunscreens</p>

Schalka¹,

Corrêa²,

Sawada³

et al. 2019

CCID

View full text Add to dashboard Cite

IntroductionThe role of visible light (VL) in the process of skin pigmentation by solar radiation has been demonstrated. Sunscreens with the presence of pigments, particularly iron oxide (IO), have a greater protective effect against VL and are, therefore, highly recommended for prevention and treatment of hyperpigmentation disorders. This study aimed to evaluate 33 sunscreen formulations, and through spectrophotometric measurements, proposes new methods to evaluate the VL protection factor and the pigmentation protection factor.Methods33 sunscreen formulations marketed in Brazil were evaluated, including 17 products containing pigments and 16 products with no pigments. Spectrophotometric measurements were taken to determine solar VL protection factor and the pigmentation protection factor, based on the absorption curve of the product, the pigmentation action spectrum and sun spectrum.ResultsSunscreen with pigments presented a higher solar VL protection factor and pigmentation protection factor compared to products without pigment. The statistical analysis showed a strong correlation between the solar VL protection factor and the integral of the absorption curve in the VL range and the transmittance reduction (%) in the same range. The correlation between the VL protection factor and the pigmentation protection factor was also demonstrated.ConclusionThe VL protection factor and the pigmentation protection factor showed to be adequate metrics to estimate the effectiveness of sunscreens in the prevention of the pigmentary effect of solar VL and the pigmentary effect of the complete spectrum of immediate pigmentation.

show abstract

“…Diffey and Osterwalder even postulated that the labelled sunscreen sun protection factor (SPFs) may overestimate protection in natural sunlight due to the greater spectral output in the visible region compared with UV solar simulation, contributing 17% to an erythemal reaction. Adding VIS‐absorbing mineral filters to sunscreens significantly improves protection against the development of VIS‐induced hyperpigmentations . However, inclusion of such mineral pigments, for example, iron oxide and non‐nano‐titanium dioxide, results in tinted formulations, limiting their broad application.…”

Section: Introductionmentioning

confidence: 99%

“…Adding VIS‐absorbing mineral filters to sunscreens significantly improves protection against the development of VIS‐induced hyperpigmentations . However, inclusion of such mineral pigments, for example, iron oxide and non‐nano‐titanium dioxide, results in tinted formulations, limiting their broad application. Recent evidence suggests that plant‐derived antioxidants can protect VIS‐exposed skin from ROS‐induced oxidative stress, but their effects on Nrf2 remain to be established.…”

Section: Introductionmentioning

confidence: 99%

High‐energy visible light at ambient doses and intensities induces oxidative stress of skin—Protective effects of the antioxidant and Nrf2 inducer Licochalcone A in vitro and in vivo

Mann

Eggers

Rippke

et al. 2019

Photoderm Photoimm Photomed

View full text Add to dashboard Cite

Background Solar radiation causes skin damage through the generation of reactive oxygen species (ROS). While UV filters effectively reduce UV‐induced ROS, they cannot prevent VIS‐induced (400‐760 nm) oxidative stress. Therefore, potent antioxidants are needed as additives to sunscreen products. Methods We investigated VIS‐induced ROS formation and the photoprotective effects of the Nrf2 inducer Licochalcone A (LicA). Results Visible spectrum of 400‐500 nm dose‐dependently induced ROS in cultured human fibroblasts at doses equivalent to 1 hour of sunshine on a sunny summer day (150 J/cm2). A pretreatment for 24 hours with 1 µmol/L LicA reduced ROS formation to the level of unirradiated cells while UV filters alone were ineffective, even at SPF50+. In vivo, topical treatment with a LicA‐containing SPF50 + formulation significantly prevented the depletion of intradermal carotenoids by VIS irradiation while SPF50 + control did not protect. Conclusion LicA may be a useful additive antioxidant for sunscreens.

show abstract

Influence of visible light on cutaneous hyperchromias: Clinical efficacy of broad‐spectrum sunscreens

Abstract: Finally, this study discusses how the combination of UV filters and pigments can protect the skin from solar radiation and reduces skin hyperpigmentations.

Cited by 32 publications

References 30 publications

Use of Advanced Imaging Techniques for the Characterization of Oily Skin

Use of Advanced Imaging Techniques for the Characterization of Oily Skin

<p>A novel method for evaluating sun visible light protection factor and pigmentation protection factor of sunscreens</p>

High‐energy visible light at ambient doses and intensities induces oxidative stress of skin—Protective effects of the antioxidant and Nrf2 inducer Licochalcone A in vitro and in vivo

Contact Info

Product

Resources

About