Influence of Transmurality, Infarct Size, and Severe Microvascular Obstruction on Left Ventricular Remodeling and Function After Primary Coronary Angioplasty

Tarantini, Giuseppe; Razzolini, Renato; Cacciavillani, Luisa; Bilato, Claudio; Sarais, Cristiano; Corbetti, Francesco; Marra, Martina Perazzolo; Napodano, Massimo; Ramondo, Angelo; Iliceto, Sabino

doi:10.1016/j.amjcard.2006.05.022

Cited by 131 publications

(90 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…[13][14][15] Since, DE-MRI showed no hyper-enhancement of the myocardium, it can be predicted that on follow-up complete reversal of the morphological abnormalities should be observed, as was seen in our case (Figure 3). …”

Section: Discussionsupporting

confidence: 73%

Magnetic resonance imaging findings in apical ballooning syndrome or takotsubo cardiomyopathy

Jambhekar

Pandey

Kaushik

et al. 2012

Indian Heart Journal

View full text Add to dashboard Cite

A B S T R A C TCardiac magnetic resonance imaging (CMRI) plays an important role in the diagnosis and followup of apical ballooning syndrome (takotsubo syndrome), a recently described cardiac condition characterised by transient dyskinesia of the left ventricle secondary to an acute emotional event.We present the CMRI findings in a 53-year-old female diagnosed with apical ballooning syndrome and discuss its value in the diagnosis and follow-up of this condition.

show abstract

Section: Discussionsupporting

confidence: 73%

Magnetic resonance imaging findings in apical ballooning syndrome or takotsubo cardiomyopathy

Jambhekar

Pandey

Kaushik

et al. 2012

Indian Heart Journal

View full text Add to dashboard Cite

show abstract

“…2,4,5,[14][15][16] In our study population, the strongest relationship between total infarct size and LVEF (r = -0.79, P < 0.01) was found in early revascularized patients (n = 10) with an infarct size ≥ 15% of the LV mass. This was also recently shown by Pride, et al, who found a similar relationship in MI patients with an infarct size ≥ 15% (r = -0.81, P < 0.001).…”

Section: Discussionmentioning

confidence: 85%

“…9) However, most previous CE-CMR studies that investigated the relationship between infarct size and cardiac remodeling did not measure the size of the peri-infarct zone. [2][3][4][5][6]8,9,[14][15][16]18,19) The only exception was a study by Heidary,et al,17) who found in a population of patients with ischemic cardiomyopathy, no significant relation between infarct tissue characteristics (including peri-infarct size) and both LV geometry and function.…”

Section: Discussionmentioning

confidence: 94%

“…[11][12][13] The effect of successful early revascularization on the relationship between infarct tissue characteristics versus LV remodeling is not completely known. While some investigators found significant correlations between infarct tissue characteristics and LV remodeling in patients with successful early revascularization, 2,4,5,[14][15][16] others found conflicting results in more heterogeneous study populations (Table I). 3,6,8,9,[17][18][19] Cardiovascular magnetic resonance (CMR) imaging in combination with the contrast enhancement (CE) technique allows accurate assessment of LV geometry and function as well as tissue characteristics such as size, heterogeneity, and transmurality of the myocardial scar.…”

mentioning

confidence: 87%

“…[3][4][5][6][7][8][9] Discrepancies between observations with different diagnostic techniques may reflect the fact that LV geometry and function after the MI result from a complex interaction of various factors, including successful early revascularization 10) which may limit unfavorable adaptive changes of the myocardium. [11][12][13] The effect of successful early revascularization on the relationship between infarct tissue characteristics versus LV remodeling is not completely known.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Relationship Between Infarct Tissue Characteristics and Left Ventricular Remodeling in Patients With Versus Without Early Revascularization for Acute Myocardial Infarction as Assessed With Contrast-Enhanced Cardiovascular Magnetic Resonance Imaging

et al. 2012

View full text Add to dashboard Cite

SummaryLeft ventricular (LV) remodeling following myocardial infarction (MI) is the result of complex interactions between various factors, including presence or absence of early revascularization. The impact of early revascularization on the relationship between infarct tissue characteristics and LV remodeling is incompletely known. Therefore, we investigated in patients with versus without successful early revascularization for acute MI potential relations between infarct tissue characteristics and LV remodeling with contrast-enhanced (CE) cardiovascular magnetic resonance (CMR). Patients with versus without successful early revascularization underwent CE-CMR for tissue characterization and assessment of LV remodeling including end-diastolic and end-systolic volumes, LV ejection fraction, and wall motion score index (WMSI). CE-CMR images were analyzed for infarct tissue characteristics including core-, peri-and total-infarct size, transmural extent, and regional scar scores. In early revascularized patients (n = 46), a larger area of infarct tissue correlated significantly with larger LV dimensions and a more reduced LV function (r = 0.39-0.68; all P ≤ 0.01). Multivariate analyses identified peri-infarct size as the best predictor of LV remodeling parameters (R 2 = 0.44-0.62). In patients without successful early revascularization (n = 47), there was no correlation between infarct area and remodeling parameters; only peri-infarct size versus WMSI (r = 0.33; P = 0.03) and transmural extent versus LVEF (r = -0.27; P = 0.07) tended to be related. A correlation between infarct tissue characteristics and LV remodeling was found only in patients with early successful revascularization. Peri-infarct size was found to be the best determinant of LV remodeling. Our findings stress the importance of taking into account infarct tissue characteristics and success of revascularization when LV remodeling is studied. (Int Heart J 2012; 53: 263-269)

show abstract

Cardiac Imaging

Abidov

Berman

2012

Cardiovascular Clinical Trials

View full text Add to dashboard Cite

Influence of Transmurality, Infarct Size, and Severe Microvascular Obstruction on Left Ventricular Remodeling and Function After Primary Coronary Angioplasty

Cited by 131 publications

References 17 publications

Magnetic resonance imaging findings in apical ballooning syndrome or takotsubo cardiomyopathy

Magnetic resonance imaging findings in apical ballooning syndrome or takotsubo cardiomyopathy

Relationship Between Infarct Tissue Characteristics and Left Ventricular Remodeling in Patients With Versus Without Early Revascularization for Acute Myocardial Infarction as Assessed With Contrast-Enhanced Cardiovascular Magnetic Resonance Imaging

Cardiac Imaging

Contact Info

Product

Resources

About