2012
DOI: 10.1093/cid/cis878
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Influence of the Timing of Cardiac Surgery on the Outcome of Patients With Infective Endocarditis and Stroke

Abstract: There is no apparent survival benefit in delaying surgery when indicated in IE patients after ischemic stroke. Further observational analyses that include detailed pre- and postoperative clinical neurologic findings and advanced imaging data (eg, ischemic stroke size), may allow for more refined recommendations on the optimal timing of valvular surgery in patients with IE and recent stroke syndromes.

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Cited by 134 publications
(84 citation statements)
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“…273 Fifty-eight patients who underwent surgery within 1 week of stroke were compared with 140 patients who underwent surgery ≥8 days after stroke. Hospital mortality was numerically but not significantly higher in the early surgery group (22.4% versus 12%).…”
Section: Valve Surgery In Patients With Prior Emboli/ Hemorrhage/strokementioning
confidence: 99%
“…273 Fifty-eight patients who underwent surgery within 1 week of stroke were compared with 140 patients who underwent surgery ≥8 days after stroke. Hospital mortality was numerically but not significantly higher in the early surgery group (22.4% versus 12%).…”
Section: Valve Surgery In Patients With Prior Emboli/ Hemorrhage/strokementioning
confidence: 99%
“…Stroke before surgical decision was also inversely associated with surgery during the index hospitalization, likely reflecting the uncertain timing and safety of surgery in patients with IE complicated by stroke. [30][31][32][33] The majority of stroke in IE occurs at the time of presentation, 34 before or soon after the initiation of antibiotic therapy. 35 Nearly one half of strokes in patients who did not have surgery despite an indication were hemorrhagic.…”
Section: Discussionmentioning
confidence: 99%