Influence of the physiological stage of Blackbelly sheep on immunological behaviour against gastrointestinal nematodes

González-Gardúño, Roberto; Gives, Pedro Mendoza de; Arellano, María Eugenia López; Aguilar-Marcelino, Liliana; Torres-Hernández, G.; Ojeda-Robertos, Nadia Florencia; Torres-Acosta, J.F.J.

doi:10.1016/j.exppara.2018.08.003

Cited by 11 publications

(5 citation statements)

References 31 publications

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“…Several studies have suggested that IgA has little value as a marker of H. contortus infection (Snoeck et al, 2006), although other studies have suggested it as a marker of susceptibility to GIN infections (Shaw et al, 2012). However, the IgA levels found herein were below the range (10%-15%) indicated for growing lambs (Gonz alez-Garduño et al, 2018). It may be that the IgA response is occurs locally rather than at the circulating level or in external secretions given that it has functions in saliva, milk, tears, bronchial mucous membranes, genital and urinary organs, and gastrointestinal tracts due to its direct protective role of mucosae, especially in the abomasum and jejune (McClure, 2008).…”

Section: Discussioncontrasting

confidence: 74%

High energy levels in the diet reduce the parasitic effect of Haemonchus contortus in Pelibuey sheep

López-Leyva

González-Gardúño

Huerta-Bravo

et al. 2020

Heliyon

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Nutritional aspects modulate the parasitological and immune response in infected sheep. The aim of the present study was to evaluate the parasitological and humoral immune response of Pelibuey sheep experimentally infected with Haemonchus contortus that were fed diets with two different energy (n ¼ 12) and protein (n ¼ 12) levels. Twenty-four Pelibuey lambs infected with H. contortus were evaluated over 12 weeks. An additional six animals were considered as a control group. Fecal egg count (FEC) was determined, in addition to packed cell volume (PCV), total plasma protein (TPP), and immunoglobulin levels (IgA, IgG, and IgM) by indirect enzymelinked immunosorbent assay (iELISA). Data were analyzed by repeated measures over time. The lambs that received a high-energy (HighE) diet had the lowest FEC (P < 0.01) regardless of whether they received a high (HighP) or low (LowP) level of protein. The effect of energy level was also observed over time: FEC values decreased and PCV and TPP values increased. Higher immunoglobulin levels were obtained for females (P < 0.05) than males yet, overall, the energy and protein levels of the diets did not affect the response of the immunoglobulins. Over time, however, an increase in IgG and IgM was observed, whereas the IgA level remained basal.

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Section: Discussioncontrasting

confidence: 74%

High energy levels in the diet reduce the parasitic effect of Haemonchus contortus in Pelibuey sheep

López-Leyva

González-Gardúño

Huerta-Bravo

et al. 2020

Heliyon

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“…The oldest sheep were found in herds from the municipality of Campeche with an average of 30.11 months (F26.6507, P0.00001) (Table 2), in these herds a lower total count of parasites was observed, while the youngest sheep were found in the municipality of Calakmul with 12.83 months, which presented a higher number of hpg (r0.254926, P0.05); in this sense, it has been suggested that young animals are more susceptible to infestation from gastrointestinal parasites, compared to older animals (González-Garduño et al, 2018).…”

Section: Prevalence Of Gastrointestinal Parasites In Sheepmentioning

confidence: 80%

Characterization of sheep production systems and their relation with gastrointestinal parasites in four municipalities of Campeche, Mexico

BAÑUELOS¹,

Rosales-Martínez²,

Fraire-Cordero³

et al. 2023

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Objective: The increase in the number of sheep in herds is accompanied many times by bad practices, which lead to nutritional deficiencies, rises in parasitism and loss of homeostasis. Therefore, gastrointestinal parasites from sheep were characterized from four municipalities of the state of Campeche. Design/methodology/approach: The number of sheep studied was 243, evaluating the body weight, body condition, coloring of the eye mucosae, age, eggs per grams of feces, and family of parasites. The data were analyzed through an ANOVA and Tukey’s means test (P<0.05), as well as Spearman’s correlation analysis using the statistical package Statistica 7. Results: Five parasite families were found (Trichostrongyloidae, Strongyloidae, Trichuridae, Eimeriidae and Anoplocephalidae). In the production systems of the municipality of Calakmul the five families of parasites were found, with a parasite load of 3,571 hpg. The family Trichostrongyloidae presented the highest frequency in the municipalities of Champotón and Calakmul with 52 and 75%, respectively. The animals with best body condition, FAMACHA© and lowest parasite load were observed in Hecelchakán. Limitations on study/implications: It is suggested to carry out a study of anthelmintic resistance, to establish a management of prevention and control of gastrointestinal parasites. Findings/conclusions: The frequency of gastrointestinal parasites is influenced by the management and the municipality of origin within the sheep production systems in the state of Campeche.

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“…These results could be due to fatigue experienced in infected sheep, or even differences in emotional response to the human stimulus during testing, however this needs more investigation. Additionally, Gonzalez-Garduno et al (2018) reported that behavior in sheep infected with gastrointestinal nematode is gestational state (pregnant vs. non-pregnant) and age dependent in that lactating ewes and lambs were more susceptible to gastrointestinal nematode compared to pregnant ewes, and lambs older than 300 days of age showed higher IgA relative to younger lambs.…”

Section: Immune Responsiveness and Behavioral Activitymentioning

confidence: 99%

Associations between immune competence phenotype and stress response in sheep

Schiller,

Monk,

Lee

et al. 2023

Front. Anim. Sci.

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Immune competence in domestic sheep is gaining more attention in genetic selection programs that seek to enhance flock immunity and animal welfare. A goal of many programs is to identify behavioral phenotypes that indicate stress-coping strength, as well as disease resilience. The current study set out to explore the relationship between immune responsiveness, physiological stress, and behavioral response among sheep that had been selected for ‘low’ (LR) or ‘high’ (HR) response to cell-mediated and antibody-mediate reactivity to a clostridial vaccine. Multiparous ewes were placed in four experiments which exposed the animals to various threats including, dog presence, human proximity, visual isolation from flock, and physical restraint. To evaluate the consistency of behavioral phenotypes, all ewes were placed in the test circuit one year later. Basal body temperature (via iButton) and serum cortisol concentrations were collected prior to and after the circuit each year. Immune group (HR vs. LR) was not found to be related to behavioral performance during the dog, human, isolation, or restraint challenge. Immune group categorization was also unrelated to pre- and post-cortisol concentrations, and the change in cortisol concentrations during testing. There was a negative relationship identified between response to visual isolation and change in cortisol response during testing, indicating that sheep which were more active or agitated during visual isolation from the flock experienced less of an increase in serum cortisol levels and were perhaps experiencing a negative, high arousal state compared to less reactive sheep (e.g., freeze behavior) (χ2(4, N=99) = 42.72, P <0.0001). There was also a post hoc, positive relationship identified between weight measurements and immune group, such that individuals with greater body weight were more likely to be in the high immune responsiveness group (P= 0.01). Specifically, for every unit increase in weight, there was a ~49% chance of being categorized in the HR group. This is relevant for selection programs because producers that seek to enhance immune responsiveness and performance may be able to select sheep that carry a greater body mass, and while not found in the present study, could lead to greater flock immunity.

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Influence of the physiological stage of Blackbelly sheep on immunological behaviour against gastrointestinal nematodes

Cited by 11 publications

References 31 publications

High energy levels in the diet reduce the parasitic effect of Haemonchus contortus in Pelibuey sheep

High energy levels in the diet reduce the parasitic effect of Haemonchus contortus in Pelibuey sheep

Characterization of sheep production systems and their relation with gastrointestinal parasites in four municipalities of Campeche, Mexico

Associations between immune competence phenotype and stress response in sheep

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