Influence of the Level of Renal Insufficiency on Endoscopic Changes in the Upper Gastrointestinal Tract

Anemia of Renal Disease

“…42,43 Studies of the prevalence of upper gastrointestinal ulceration in humans with CKD yield conflicting results, although recent evidence suggests that CKD patients do not have a higher prevalence of ulceration compared with patients with normal kidney function. [43][44][45][46] Although gastrin, a hormone responsible for stimulating hydrochloric acid secretion in the stomach, is cleared by the kidneys, and gastrin concentration in the blood is elevated in people and cats with CKD, hyperacidity and gastric ulceration are variably present. [47][48][49] Gastric pathology is common in dogs with kidney disease, but ulceration is uncommon; 50 similar studies in cats are lacking.…”

Upper Digestive Endoscopic Lesions in Chronic Kidney Disease (CKD): Experience of a Senegalese Center; About 50 Cases

“…However, the influence of the degree of CKD on the occurrence of gastritis is variously appreciated. Stolic did not find influence while Mitchell found gastritis in all patients with severe stages of CKD [6,7]. Gastritis often noted in uremic patients, has often been reported to cause bleeding [8,9].…”

Diyaliz Hastalarnda Üst Gastrointestinal Sistem Hastalıkları

“…Studies in uremic patients on maintenance hemodialysis also revealed conflicting data with increased prevalence of gastroduodenal lesions (e.g., gastritis, duodenitis, and peptic ulcers) reported in some studies, whereas the prevalence was found to be similar to the general population in others (6,8). Notably, neither the severity of renal dysfunction nor the duration of hemodialysis was shown to be correlated with the prevalence of gastrointestinal lesions in patients with chronic renal failure (8,19).…”