Influence of the Extraction Method on the Yield of Flavonoids and Phenolics from Sideritis spp. (Pirin Mountain tea)

Alipieva, Kalina; Petreska, Jasmina; Gil‐Izquierdo, Ángel; Стефова, Марина; Evstatieva, L.; Bankova, Vassya

doi:10.1177/1934578x1000500113

Cited by 30 publications

(37 citation statements)

References 7 publications

(7 reference statements)

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“…In our previous study, chemical characterization of Sideritis scardica and Sideritis raeseri decoction has been successfully performed using HPLC/DAD/ESI/MS n and 35 major polyphenolic constituents were identified [6,7,11,12]. In the present study, identification of these compounds and their conjugated forms in human urine after ingestion of S. scardica decoction was carried out.…”

Section: Introductionmentioning

confidence: 87%

Characterization of urinary bioactive phenolic metabolites excreted after consumption of a cup of mountain tea (Sideritis scardica) using liquid chromatography – tandem mass spectrometry

Станоева

Bagashovska

Стефова

2012

Maced. J. Chem. Chem. Eng.

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A nutrition experiment was performed for studying the bioavailability of polyphenols from Sideritis with healthy human subjects, who consumed a standardized Sideritis decoction after which urine was collected and analyzed. 35 polyphenolic compounds in the ingested decoction and 63 of their metabolites in urine collected after ingestion were identified using HPLC/MSn. It was shown that polyphenols present in Sideritis decoction are extensively conjugated to glucuronides, sulfates and also transformed to methylated forms after oral administration. In the analyzed urine samples, 31 different metabolites of hypolaetin, methylhypolaetin, isoscutellarein, methylisoscutellarein and apigenin, and 32 phenolic acids metabolites were detected, hypolaetin and isoscutellarein metabolites being the most abundant. This enabled polyphenols metabolites patterns to be obtained, which is a crucial step towards revealing the bioavailability and metabolism of phenolic compounds from Sideritis in human. The identification and structure elucidation of these metabolites provided essential data for further studies of Sideritis polyphenols bioavailability.

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Section: Introductionmentioning

confidence: 87%

Characterization of urinary bioactive phenolic metabolites excreted after consumption of a cup of mountain tea (Sideritis scardica) using liquid chromatography – tandem mass spectrometry

Станоева

Bagashovska

Стефова

2012

Maced. J. Chem. Chem. Eng.

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“…The moisture present in the cell matrix results in the sudden rise in temperature locally due to the absorption of microwave energy [3] causing cell rupture. Microwave absorption also results in the increase of solubility [42]. Hence increased solubility and improved solute-solvent contact due to the rupture of the cell enhances the mass transfer from solid to liquid phase.…”

Section: Kinetics Of Maementioning

confidence: 97%

Microwave assisted extraction of flavonoids from Terminalia bellerica: Study of kinetics and thermodynamics

Krishnan

Rajan

2016

Separation and Purification Technology

119

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“…Recently, UAE had been widely for extraction of sesquiterpene,[5] flavonoids,[6] phenolics,[7] and polysaccharide,[8] etc.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound-assisted extraction of total flavonoids from Inula helenium

Jin¹,

Zhao²,

Guo³

et al. 2012

Phcog Mag

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Background:Inula helenium was a perennial herb belonging to composite family and the roots of I. helenium have been widely used in traditional Chinese medicine. In this study, I. helenium was used as an experimental matrix.Materials and Methods:Ultrasound-assisted extraction (UAE) of total flavonoids from I. helenium was studied with dual wavelength UV-VIS spectrophotometer. Effects of various factors including ratio of material to liquid, ultrasonic time, ethanol concentration and extraction times on extraction yield of total flavonoids were evaluated. Then, orthogonal design of four factors at three levels was applied for optimization the extraction yields of flavonoids from the root of I. helenium.Result:The optimal extracting process of the total flavonoids from the root of the I. helenium was 1 g plant sample with 20 ml of 60% ethanol, extracting twice and each time for 20 min.Conclusion:Under these optimal conditions, the yield of total flavonoids was (17.36±0.94) mg/g. UAE was more efficient and time saving for the extraction of flavonoids from plant materials.

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Influence of the Extraction Method on the Yield of Flavonoids and Phenolics from Sideritis spp. (Pirin Mountain tea)

Cited by 30 publications

References 7 publications

Characterization of urinary bioactive phenolic metabolites excreted after consumption of a cup of mountain tea (Sideritis scardica) using liquid chromatography – tandem mass spectrometry

Characterization of urinary bioactive phenolic metabolites excreted after consumption of a cup of mountain tea (Sideritis scardica) using liquid chromatography – tandem mass spectrometry

Microwave assisted extraction of flavonoids from Terminalia bellerica: Study of kinetics and thermodynamics

Ultrasound-assisted extraction of total flavonoids from Inula helenium

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