Influence of Temperature on Drosophila Alcohol Dehydrogenase Polymorphism

Studies of esterase 6 in Drosophila melanogaster XII. Evidence for temperature selection of Est 6 and Adh alleles

“…The increase in Adhfin cage populations at cool temperatures has been found by other investigators (Alahiotis & Pelecanos, 1980;Oakeshott, 1979) and corresponds to the strong latitudinal and altitudinal correlations of Adh/ with cool temperature in natural populations (Vigue & Johnson, 1973;Pipkin et al, 1973;Malpica & Vassallo, 1980). High ethanol concentrations also select for the Adhf allele (Cavener & Clegg, 1978;Van Delden et aL, 1978).…”

Ethanol tolerance, alcohol-dehydrogenase activity and Adh allozymes in Drosophila melanogaster

“…In the case of the alcohol-dehydrogenase (Adh) locus in Drosophila, however, there is now substantial agreement that the differences between alleles at this locus can have adaptive significance in a number of species (Gibson, 1970;Clarke, 1975;David, 1977;Starmer et al, 1977;Fontdevila et al, 1980;Knoppien et al, 1980). Thus in D. melanogaster, the frequently reported clines in Adh allele frequencies apparently have a selective origin (Pipkin et aL, 1973), whereby one agent of selection is temperature, a temperature-correlated variable perhaps relating to resources, or a combination of the two (Malpica & Vassalo, 1980). Considering resources, in polymorphic populations the Adh F allele is often favoured in the presence of alcohol (Gibson, 1970;Cavener & Clegg, 1978).…”

Allozyme variation in fourteen natural populations of Drosophila melanogaster collected from different regions of France

“…Allozyme variation was studied by starch gel electrophoresis using P OULIK ' S discontinuous buffer system (P OULIK , 1957 (G ROSSMAN B t al., 1970 ;PIPKIN et al, 1973) fig. 1) show a more or less high level of variability at the 6 loci studied (table 1 ).…”