Aiming at the requirement of accurate simulation of near-space atmospheric infrared background radiation, this paper simulates near-space infrared atmospheric background radiance according to atmospheric parameters detected by satellites.The multi-channel infrared radiometer SABER (Sound of the Atmosphere using Broadband Emission Radiometry) carried by TIMED satellite (Thermosphere, Ionosphere Mesosphere Energetics and Dynamics) is used to acquire atmospheric profile. Combined with limb observation model and atmospheric background radiance calculation model, the transmittance and spectral radiance of infrared atmospheric background were simulated. The spectral radiance of atmospheric background under the standard atmospheric model and satellite atmospheric profiles was compared to analyze the difference between the two atmospheric parameter. In the infrared band, the atmospheric profile has a great impact on atmospheric background radiance. For the accurate simulation calculation of infrared background spectral radiance in different regions, the influence of atmospheric profile parameters should be taken into account.