Influence of symptoms of depression on the quality of life of men diagnosed with prostate cancer

Abstract

Objective: to evaluate the prevalence of symptoms of depression among men diagnosed with prostate cancer and their association with quality of life and treatment-related factors. Methods: a cross-sectional study of 85 men with a mean age of 66±8 years who were diagnosed with prostate cancer was performed. The survey was based on a questionnaire with previously validated instruments which investigated social, demographic and economic characteristics, the history of the disease, quality of life (European Organization for Research and Treatment of Cancer Questionnaire C30 - EORTC QLQ-C30 / QLQ-PR25) and symptoms of depression (Beck Depression Inventory). The presence of symptoms of depression was considered an outcome, and statistical analyzes were performed using the Chi-square test, Fisher's exact test, Mann Whitney U test and Poisson regression (p<0.05). Results: significant results were found for quality of life in relation to symptoms of depression in the functional, global and symptomatic health scale (p<0.001). This demonstrates that the presence of symptoms of depression is related to a negative quality of life. Conclusions: for a greater understanding of prostate cancer and its consequences on the quality of life of patients it is important to consider possible disorders in psychological aspects caused by the illness, as symptoms of depression are frequent in patients undergoing treatment for prostate cancer.

Depression, Anxiety, and Their Association to Health-Related Quality of Life in Men Commencing Prostate Cancer Treatment at Tertiary Hospitals in Cape Town, South Africa

“…52,53 Seeman et al, 2018 showed that depressive symptoms had a significant negative effect on the QOL of men with CaP. 54 We were unable to account for the correlation between the CES-D and STAI-S with HRT symptoms despite participants not being exposed to ADT. It is possible that this may in part be attributed to late onset hypogonadism (LOH).…”

Influence of Physical Activity in Patients with Prostate Cancer Undergoing Radiotherapy and/or Hormonal Deprivation Therapy: Integrative Literature Review

“…Although survival rates have risen and advances in diagnosis and treatment have been made, cancer is still received as a death sentence and brings with it psychological consequences such as fear, sadness and depression [5]. In addition, it is known that there are complications from prostate cancer treatment that can have an impact on urinary and sexual function, such as urinary incontinence and erectile dysfunction that affect marital life and generate losses in the quality of life of patients, including the psychological aspect [6].…”

Alterações moleculares no desenvolvimento do câncer de próstata

“…A depressão é uma das principais repercussões psicológicas que interferem na qualidade de vida dos homens acometidos pelo CP, pois, além da repercussão clínica, o paciente convive diariamente com a dor física e risco de morte relativos à ocorrência de possíveis metástases e recorrência da doença. Além disso, o medo da impotência sexual, angústia da perda de controle urinário, incapacidade de ter ereções satisfatórias e insegurança de ser abandonado pela parceira/o sexual; são alguns sentimentos expressos pelos pacientes com CP, afetando a qualidade de vida no que diz respeito à saúde física e emocional desses homens (Seemann et al, 2018).…”