In this study, sulfate removal by ion exchange method using Purolite A200 resin was investigated. In the study, the effect of resin amount, temperature, initial pH of the solution, initial sulfate concentration of the solution and mixing speed were selected as parameters. As a result, in sulfate removal; it was observed that the initial pH value was not very effective, but the temperature, initial sulfate concentration, mixing speed and resin amount were effective and the removal efficiency increased with the increase in the values of these parameters. The qm value was found as -0.381, while the Langmuir coefficient KL value was found as -0.227. For Freundlich isotherm, the Kf value was found to be 0.617, while the n coefficient value was found to be 0.705. These result was show that Langmuir isotherm was found to be a more suitable adsorption isotherm than Freundlich isotherm for this system.