Influence of stent-induced vessel deformation on hemodynamic feature of bloodstream inside ICA aneurysms

Abstract

One of the effective treatment options for intracranial aneurysms is stent-assisted coiling. Though, previous works have demonstrated that stent usage would result in the deformation of the local vasculature. The effect of simple stent on the blood hemodynamics is still uncertain. In this work, hemodynamic features of the blood stream on four different ICA aneurysm with/without interventional are investigated. To estimate the relative impacts of vessel deformation, four distinctive ICA aneurysm is simulated by the one-way FSI technique. Four hemodynamic factors of aneurysm blood velocity, wall pressure and WSS are compared in the peak systolic stage to disclose the impact of defamation by the stent in two conditions. The stent usage would decrease almost all of the mentioned parameters, except for OSI. Stenting reduces neck inflow rate, while the effect of interventional was not consistent among the aneurysms. The deformation of an aneurysm has a strong influence on the hemodynamics of an aneurysm. This outcome is ignored by most of the preceding investigations, which focused on the pre-interventional state for studying the relationship between hemodynamics and stents. Present results show that the application of stent without coiling would improve most hemodynamic factors, especially when the deformation of the aneurysm is high enough.

The influence of sac centreline on saccular aneurysm rupture: computational study

“…The reported value in this study is for the peak systolic condition, which is of particular importance 29 – 31 .

Figure 2 Applied mass flow rate and pressure profile at inlet and outlets 1 .

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“…However, with advances in medical imaging technology over the last three decades, more than 50% of cerebral aneurysms are now detected before rupture occurs. This has provided researchers with access to valuable data and information about the geometric characteristics of aneurysms, which is essential for selecting appropriate treatments 1 – 3 .…”

A Comprehensive Numerical Approach to Coil Placement in Cerebral Aneurysms: Mathematical Modeling and In Silico Occlusion Classification

“…They show that a more comprehensive model of the clotting cascade results in more realistic thrombus growth when compared to simplified models. The influence of stent induced vessel deformation on the hemodynamics of intracranial aneurysms is investigated in (Sabernaeemi et al, 2023). Here the computational fluid dynamics methods provide new insight into the flow patterns triggered by stent assisted coiling and show that the deformation of the aneurysm considerably decreases the wall shear stress on the aneurysm wall due to limited entrance of blood into the aneurysm.…”

Impacts of morphology parameters on the risk of rupture in intracranial aneurysms: statistical and computational analyses

“…Advances in medical imaging techniques, such as computed tomography angiography (CTA) and magnetic resonance angiography (MRA), have enabled clinicians and researchers to accurately assess aneurysm geometrical features and study their relationship with hemodynamic characteristics 22 , 23 . Computational fluid dynamics (CFD) simulations have emerged as valuable tools to model blood flow within aneurysms and quantify the WSS and OSI distribution 24 – 26 .…”