Usefulness of transcutaneous Doppler jugular venous echo to predict pulmonary hypertension in COPD patients. W. Matsuyama, R. Ohkubo, K. Michizono, M. Abe, Y. Nakamura, M. Kawabata, M. Osame. #ERS Journals Ltd 2001. ABSTRACT: Pulmonary hypertension is an important factor that determines the prognosis of chronic obstructive pulmonary disease (COPD) patients. Echocardiography is a noninvasive and useful bedside method for measurement of pulmonary artery pressure. However, this method is sometimes difficult because of the overinflated lungs in COPD patients. This study attempted to estimate pulmonary hypertension in COPD patients using transcutaneous Doppler jugular vein flow velocity recording.The mean pulmonary artery pressure (MPAP) of 64 COPD patients was examined using cardiac catheterization. The right jugular vein flow velocity was measured within 24 h using transcutaneous Doppler echo, after which the ratio of diastolic flow (Df) and systemic flow (Sf) velocity was calculated. Subsequently, the statistical correlation of MPAP and the Df/Sf ratio was examined. MPAP was also measured using standard cardiac echo methods and the results were compared.The Df/Sf velocity ratio showed significant correlation with MPAP in COPD patients (r~0.844, pv0.0001). The sensitivity was 71.4%, and the specificity 95.3% (cut-off ratio~1.0). Jugular venous Doppler echo could be performed in all patients while other cardiac echo methods could not be performed in all patients. The specificity of the methods used was higher than other cardiac echo methods.Transcutaneous jugular vein flow velocity measurement may be applicable to bedside prediction of pulmonary hypertension in chronic obstructive pulmonary disease patients. [6,7]. However, these methods have some disadvantages, namely: 1) right-sided cardiac catheterization is invasive; 2) echocardiography is sometimes difficult in COPD patients because of the overinflated lungs; 3) the specificity and sensitivity of electrocardiography is low [8]; and 4) myocardial scintigraphy is expensive. In 1989, RANGANATHAN and SIVACIYAN [9] reported the usefulness of transcutaneous Doppler jugular venous flow velocity recording to estimate pulmonary artery pressure in patients with cardiac disorders but this method was not investigated in COPD patients. This study measured mean pulmonary artery pressure (MPAP) in COPD patients using the previous methods and investigated the predicted value of transcutaneous Doppler jugular venous flow velocity recording. This method was found to be applicable for bedside prediction of pulmonary hypertension in COPD patients.
Patients and methodsThis study investigated 64 COPD patients (60 males) who were admitted to the Third Dept of Internal Medicine (Kagoshima University School of Medicine) and the Dept of Cardiology (NakamuraOnsen Hospital). Fifty-nine patients were suffering from emphysema while others had chronic bronchitis. All patients gave their written consent to participate in this study. All patients with tachycardia, arrythmia, infectious disor...