Influence of replacing oregano essential oil by ground oregano leaves on chitosan/alginate-based dressings properties

Improvement of the Antimicrobial Activity of Oregano Oil by Encapsulation in Chitosan—Alginate Nanoparticles

“…Presented in percentage, the minimal inhibitory concentration (MIC) of OrO ranged depending on the strain from 0.05% to 6.23% [8,18] in broth model systems (test microorganisms S. aureus, E. faecalis, E. coli, K. pneumonia, and P. aeruginosa) and from 1% to 5% (a large set of food-borne pathogens) when the disk diffusion method was preferred as the evaluation model [10]. A recent study by Sobczyk et al [24] reported high antibacterial activity of oregano oil and oregano leaves on chitosan-alginate-based dressings for the treatment of wounds. The active concentrations of oregano oil on S. aureus and E. coli were 0.25% and 0.5% for both strains whereas oregano leaves exerted an equivalent antimicrobial potential at the concentrations of 10% and 20%.…”

“…Recent preclinical pharmacological studies on the therapeutic properties of OrO and both of the main molecules in its composition, the terpenoid thymol and its phenol isomer carvacrol, have demonstrated a wide spectrum of pharmacological activities such as antibacterial [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24], antifungal [22,23,25,26], antiviral [27][28][29][30], antioxidant, etc. According to the published data, OrO, carvacrol, and thymol exert a bacteriostatic or bactericidal effect in a concentration-dependent manner against food-borne pathogens, human or animal clinical isolates, including a broad spectrum of Gram-positive (Staphylococcus spp., Streptococcus spp., Enterococcus spp., Acinetobacter spp., Bacillus spp., Listeria monocytogenes, etc.)…”

Atividade antimicrobiana da quitosana associada a óleos essenciais na aplicação biomédica: uma revisão integrativa

“…Através da análise dos resultados dos artigos selecionados, foi possível verificar que os biomateriais contendo quitosana, sem a adição de óleos essenciais, já apresentaram potencial antimicrobiano frente a algumas cepas microbianas (Amalraj et al, 2020;Espíndola Sobczyk et al, 2021;Râpă et al, 2021;Santos et al, 2019). Sabe-se que existem inúmeros fatores que influenciam a atividade antimicrobiana da quitosana e, dentre os principais, citam-se a massa molar, o grau de desacetilação e o pH do meio (Matica et al, 2019;Riaz Rajoka et al, 2020).…”

“…Aliado aos benefícios da quitosana, a associação desse biopolímero aos óleos essenciais também é bastante promissor (Espíndola Sobczyk et al, 2021;Santos et al, 2019). Os óleos essenciais são misturas de compostos voláteis caracterizados por um forte aroma, extraídos de plantas e/ou especiarias (Amalraj et al, 2020;Orchard et al, 2017;Santos et al, 2019).…”

Combined Effect of Impregnation with an Origanum vulgare Infusion and Osmotic Treatment on the Shelf Life and Quality of Chilled Chicken Fillets

“…From an economic perspective, using dried ground leaves of oregano could be advantageous in an effort to reduce the necessary processing and the high costs of oil extraction as long as the antimicrobial properties of such dry matter could be established. Sobczyk et al [ 31 ] showed that although the content of active compounds thymol and carvacrol was lower in ground leaves as compared to the essential oil, there was an evident antibacterial activity of this oregano form against gram-positive and gram-negative bacteria, confirming the beneficial effect of the bioactive components of this plant. Detailed determination of bioactive compounds present in dried oregano leaves is provided in [ 32 ] where authors investigated alternative extraction methods.…”