Influence of repetitive transcranial magnetic stimulation on tibialis anterior activity during walking in humans

Rambour, M.; Caux-Dedeystere, Alexandre; Devanne, H.; Defebvre, Luc; Derambure, Philippe; Delval, Arnaud

doi:10.1016/j.neulet.2016.01.027

Cited by 4 publications

(3 citation statements)

References 48 publications

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“…Similarly, the effects of TBS over the motor cortex of the upper limb are known to be modulated or even blocked by muscle activation that occurs around the time of TBS stimulation ( Huang et al, 2008 ; Goldsworthy et al, 2012 ; Huang, 2016 ). Furthermore, Rambour et al (2016) showed that application of iTBS after walking fails to increase motor cortex excitability in the TA muscle. On the other hand, Geertsen et al (2011) reported that spinal interneuronal pathways modify the descending commands to spinal motor neurons and influence the MEP amplitudes elicited by TMS.…”

Section: Discussionmentioning

confidence: 99%

Priming With Intermittent Theta Burst Transcranial Magnetic Stimulation Promotes Spinal Plasticity Induced by Peripheral Patterned Electrical Stimulation

et al. 2018

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This study explored the effect of corticospinal activity on spinal plasticity by examining the interactions between intermittent theta burst transcranial magnetic stimulation (iTBS) of the motor cortex and peripheral patterned electrical stimulation (PES) of the common peroneal nerve (CPN). Healthy volunteers (n = 10) received iTBS to the tibialis anterior (TA) muscle zone of the motor cortex and PES of the CPN in three separate sessions: (1) iTBS-before-PES, (2) iTBS-after-PES, and (3) sham iTBS-before-PES. The PES protocol used 10 100-Hz pulses every 2 s for 20 min. Reciprocal inhibition (RI) from the TA to soleus muscle and motor cortical excitability of the TA and soleus muscles were assessed at baseline, before PES, and 0, 15, 30, and 45 min after PES. When compared to the other protocols, iTBS-before-PES significantly increased changes in disynaptic RI for 15 min and altered long-loop presynaptic inhibition immediately after PES. Moreover, the iTBS-induced cortical excitability changes in the TA before PES were correlated with the enhancement of disynaptic RI immediately after PES. These results demonstrate that spinal plasticity can be modified by altering cortical excitability. This study provides insight into the interactions between modulation of corticospinal excitability and spinal RI, which may help in developing new rehabilitation strategies.

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Section: Discussionmentioning

confidence: 99%

Priming With Intermittent Theta Burst Transcranial Magnetic Stimulation Promotes Spinal Plasticity Induced by Peripheral Patterned Electrical Stimulation

et al. 2018

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“…Recently, EEG recorded from the leg area of M1 and EMG recorded from ankle plantar flexor muscles have shown coupled gamma oscillations in the stance phase during treadmill walking [74]. Our group has also demonstrated that either excitatory or inhibitory repetitive transcranial magnetic stimulation of M1 was unable to change the level of activity of the leg muscles during gait contrary to what is observed for simple upper limb movements, suggesting a more complex role of M1 than simply controlling muscle tone during gait [75]. [61], the head model was created from a standard MRI template and the boundary element method was used for calculating the leadfield matrix, whereas cortical sources were reconstructed thanks to weighted minimum-norm estimates before projecting the obtained dipole sources on 68 cortical regions from the Desikan-Killiany atlas.…”

Section: Cortical Oscillations During Gait In Healthy Subjectsmentioning

confidence: 65%

Cortical Oscillations during Gait: Wouldn’t Walking Be So Automatic?

et al. 2020

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Gait is often considered as an automatic movement but cortical control seems necessary to adapt gait pattern with environmental constraints. In order to study cortical activity during real locomotion, electroencephalography (EEG) appears to be particularly appropriate. It is now possible to record changes in cortical neural synchronization/desynchronization during gait. Studying gait initiation is also of particular interest because it implies motor and cognitive cortical control to adequately perform a step. Time-frequency analysis enables to study induced changes in EEG activity in different frequency bands. Such analysis reflects cortical activity implied in stabilized gait control but also in more challenging tasks (obstacle crossing, changes in speed, dual tasks . . . ). These spectral patterns are directly influenced by the walking context but, when analyzing gait with a more demanding attentional task, cortical areas other than the sensorimotor cortex (prefrontal, posterior parietal cortex, etc.) seem specifically implied. While the muscular activity of legs and cortical activity are coupled, the precise role of the motor cortex to control the level of muscular contraction according to the gait task remains debated. The decoding of this brain activity is a necessary step to build valid brain-computer interfaces able to generate gait artificially.

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“…TBS has been applied over the motor cortex using a leg muscle as a dosing reference, with no reports of adverse events. 107,110,111 Some scientists have debated whether the MT is an appropriate measure for the dose estimation of some brain regions, particularly the cerebellum. 78,112 Although it captures neuronal excitability and can be easily implemented in clinical and research settings, it indicates the excitability of the motor cortex only.…”

Section: Are These Parameters Sufficient?mentioning

confidence: 99%

Safety Considerations for Cerebellar Theta Burst Stimulation

Hurtado-Puerto

Nestor

Eldaief

et al. 2020

Clinical Therapeutics

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Purpose: The cerebellum is an intricate neural structure that orchestrates various cognitive and behavioral functions. In recent years, there has been an increasing interest in neuromodulation of the cerebellum with transcranial magnetic stimulation (TMS) for therapeutic and basic science applications. Theta burst stimulation (TBS) is an efficient and powerful TMS protocol that is able to induce longerlasting effects with shorter stimulation times compared with traditional TMS. Parameters for cerebellar TBS are traditionally framed in the bounds of TBS to the cerebral cortex, even when the 2 have distinct histologic, anatomical, and functional characteristics. Tolerability limits have not been systematically explored in the literature for this specific application. Therefore, we aimed to determine the stimulation parameters that have been used for cerebellar. TBS to date and evaluate adverse events and adverse effects related to stimulation parameters.Methods: We used PubMed to perform a critical review of the literature based on a systematic review of original research studies published between September 2008 and November 2019 that reported on cerebellar TBS. We recovered information from these publications and communication with authors about the stimulation parameters used and the occurrence of adverse events.Findings: We identified 61 research articles on interventions of TBS to the cerebellum. These articles described 3176 active sessions of cerebellar TBS in 1203 individuals, including healthy participants and patients with various neurologic conditions, including 2020 Elsevier HS Journals, Inc.

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Influence of repetitive transcranial magnetic stimulation on tibialis anterior activity during walking in humans

Cited by 4 publications

References 48 publications

Priming With Intermittent Theta Burst Transcranial Magnetic Stimulation Promotes Spinal Plasticity Induced by Peripheral Patterned Electrical Stimulation

Priming With Intermittent Theta Burst Transcranial Magnetic Stimulation Promotes Spinal Plasticity Induced by Peripheral Patterned Electrical Stimulation

Cortical Oscillations during Gait: Wouldn’t Walking Be So Automatic?

Safety Considerations for Cerebellar Theta Burst Stimulation

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