Influence of Radiation-induced Chromosomal Aberrations on the Viability of Tumour and Normal Mammalian Cells Method of Biological Dosimetry

Chromosome Aberrations in Leukocytes Exposed in Vitro to Diagnostic Levels of X-Rays

“…Any chromosomal aberration resulting in an excess or a deficit of genetic material in a germ cell could be responsible for a defective embryo. A single somatic cell with an alteration in chromosomal material is usually of little detriment to the developed individual, since the most likely fate of the progeny of that cell is nonviability (Shapiro et al, 1963). Normal persons exposed to accidental irradiation in Bender and Gooch's study (1963) have been carrying many millions of abnormal leukocyte chromosomes in their bodies for years with no apparent ill effect.…”