Influence of Probiotic Bacteria Lactobacillus Rhamnosus L108 on Host Gene Expression (In the Caenorhabditis Elegans Model).

Abstract

The article presents a study of the effect of the probiotic bacterium Lactobacillus rhamnosus L108 on the expression of host longevity genes in the Caenorhabditis elegans model. The study found that the Lactobacillus rhamnosus L108 strain increased the lifespan of Caenorhabditis elegans by 9.6%. Also, when analyzing longevity genes, an increase in the level of expression of the sir-2.1, skn-1, and daf-16 genes, which underlie the regulation of conservative signaling protective pathways of insulin/insulin-like factor-1 and p38 MAPK, was observed.