Influence of pregnancy on cardiac function and hemodynamics in women with Ebstein's anomaly

Kushima, Miki; Inai, Kei; Shinohara, Tokuko; Shimada, Eriko; Shimizu, Mikiko; Tomimatsu, Hirofumi; Ogawa, Masaki; Nakanishi, Toshio

doi:10.1111/aogs.13373

Cited by 9 publications

(9 citation statements)

References 17 publications

(40 reference statements)

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“…As a result, pregnant patients should be closely monitored, and appropriate interventions should be carried out based on the severity of their complications. Also increased rates of adverse fetal outcomes especially low birth weight and prematurity in women with diverse types of heart disease have been observed in literatures (21). Low cardiac output and cyanosis are risk factors for adverse fetal outcomes.…”

Section: Discussionmentioning

confidence: 96%

“…The Japan Circulation Society guidelines (28) suggest that elective CS should be considered for women who have cyanosis, uncontrolled arrhythmias or unstable hemodynamics. However, although it is difficult to evaluate objectively the symptoms associated with right heart failure that characterize Ebstein's anomaly, it is important to select the appropriate mode of delivery (21). In this present study both first and second case Caesarean delivery was done due to obstetrician indication and patient's preference.…”

Section: Discussionmentioning

confidence: 97%

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Title: How to manage Ebstein’s anomaly in pregnancy: Literature Review with case study

Nematollahi,

Movahedi,

Bahrami

et al. 2024

Preprint

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Objectives of the review: Ebstein’s anomaly (EA) is an uncommon, congenital heart malformation that occurs in 1% of congenital heart disease cases. Depending on the severity of anatomical malformations, and haemodynamic consequence, also some anomalies which are associated with EA, natural history and the clinical presentation of patients is extremely variable. How to manage these patients during pregnancy or approach to patients who are planning to become pregnant is an important issue. Methods used to conduct the review: Here, we review of the literatures existing on this subject to discuss how to approach to Ebstein’s anomaly in pregnancy or known patients who plans for pregnancy also report three different real cases of Ebstein’s anomaly in pregnancy for better description this subject. Findings of the review: Pregnancy in Ebstein’s anomaly, is well tolerated most of the time, However, the maternal risks of pregnancy co-relate well with the severity of anatomical malformations also presence of cyanosis or simultaneous other cardiac anomalies. Interpretations and implications of the findings: Pregnant patients with complex congenital heart disease requires close follow up in expert centers. This manuscript provides excellent examples of well managed patients that may help the clinicians for approach to theses patient specially in preconception visit

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Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 97%

Title: How to manage Ebstein’s anomaly in pregnancy: Literature Review with case study

Nematollahi,

Movahedi,

Bahrami

et al. 2024

Preprint

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“…EA is cyanotic congenital heart disease of the tricuspid valve and is mainly caused by malformation of the Atrioventricular valve leading to a large atrial chamber in contrast to the ventricle of the right side. This anomaly is expected in 1 of every 200,000 births (Kanoh et al, 2018;Sharma et al, 2018;Sharma et al, 2020). Characterization of the disease is commonly recognized with clinical findings of tricuspid leaflet displacement, another additional finding such as atrial septal defect (ASD) or a patent foramen ovale (PFO), and abnormal conduction system presented with an accessory pathway (Kanoh et al, 2018;N.…”

Section: Introductionmentioning

confidence: 99%

“…This anomaly is expected in 1 of every 200,000 births (Kanoh et al, 2018;Sharma et al, 2018;Sharma et al, 2020). Characterization of the disease is commonly recognized with clinical findings of tricuspid leaflet displacement, another additional finding such as atrial septal defect (ASD) or a patent foramen ovale (PFO), and abnormal conduction system presented with an accessory pathway (Kanoh et al, 2018;N. Sharma et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

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Late diagnosis of Ebstein anomaly after pregnancy: A rare case report

Lesmana,

Ramadhan,

Barri

et al. 2024

Qanun Medika

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Congenital heart disease is a concerning disease among those affected since it affects the patient's quality of life. One of which is Ebstein Anomaly (EA), with a prevalence of 1 in 200,0000 births with a clinical characteristic of displacement of the tricuspid valve that causes atrialization of the right-side heart. Women of childbearing age are at risk because they especially have asymptomatic EA, compromised to hemodynamic consequences, and risk of maternal complications. A 25-year-old woman visited the emergency department with worsening shortness of breath since last week, during rest, accompanied by decreased physical activity tolerance, bilateral ankle edema, cyanosis to the lips, and nail bed. She had echocardiography and cardiac multi-slice computed tomography to identify EA before and after her first child's birth. She was well controlled with a loop diuretic, phosphodiesterase type 5 inhibitor, and beta-blocker but could not care for her child due to her condition. The patient was discharged after symptoms subsided, awaiting further interventional evaluation. Although EA is rare, it has high morbidity and mortality, especially in women of childbearing age since it may be asymptomatic during childhood. Therefore, early recognition of EA is probably necessary for women who are planning pregnancy.

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