Influence of polystyrene nanoparticles on the toxicity of tetrabromobisphenol A in human intestinal cell lines
Patricia Soto-Bielicka,
Ana Peropadre,
Soledad Sanz-Alférez
et al.
Abstract:Research and regulatory efforts in toxicology are increasingly focused on the development of suitable non-animal methodologies for human health risk assessment. In this work we used human intestinal Caco-2 and HCT29/MTX cell lines to address the potential risks of mixtures of the emerging contaminants tetrabromobisphenol A (TBBPA) and commercial polystyrene nanoparticles (PSNPs). We employed different in vitro settings to evaluate basal cytotoxicity through three complementary endpoints (metabolic activity, pl… Show more
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