Influence of plant extracts mixed with endodontic sealers on the growth of oral pathogens in root canal: An in vitro study

Saha, Sonali; Dhinsa, Gurpreet; Ghoshal, Ujjala; Hussain, Amrin Nayani Fatima Afzal; Nag, Soumyabrata; Garg, Ankit

doi:10.4103/jisppd.jisppd_66_18

Cited by 16 publications

(6 citation statements)

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“…Licorice, Bakul and Guguchi added to the commercial root canal sealers Significant inhibition of bacterial growth Efficient antimicrobial [62] Amla, Miswak and Nutmeg added to the commercial sealers Rich source of bioactive compounds that possess antimicrobial properties Produces bacterial inhibitory zones [63] Cinnamon oil Maximum zone of bacterial inhibition Inherently antimicrobial [64] Moringa root Acceptable physical properties when mixed with commercially available endodontic sealers [65] Tamarillo skin extract Inhibition of Enterococcus faecalis bacterial growth [66] Propolis and Green tea More effective in inhibiting bacterial growth [67]…”

Section: Herbal Materials Characteristics Referencesmentioning

confidence: 99%

Herbal Medications in Endodontics and Its Application—A Review of Literature

et al. 2022

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Herbal products are gaining popularity in dental and medical practice nowadays due to their biocompatibility, higher antimicrobial activity, antioxidant and anti-inflammatory properties. Herbal medicine has experienced rapid growth in recent years due to its beneficial properties, ease of availability, and lack of side effects. As pathogenic bacteria become more resistant to antibiotics and chemotherapeutic agents, researchers are becoming more interested in alternative products and treatment choices for oral diseases. As a result, natural phytochemicals separated from plants and utilized in traditional medicine are suitable substitutes for synthetic chemicals. The aim of this review article is to list and understand several herbal alternatives that are currently accessible for use as efficient endodontic medicaments. The herbal products used in endodontics have several advantages, including safety, ease of use, increased storability, low cost, and a lack of microbial tolerance. However, preclinical and clinical testing and interactions with other materials and adverse effects are required for these herbal products.

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Section: Herbal Materials Characteristics Referencesmentioning

confidence: 99%

Herbal Medications in Endodontics and Its Application—A Review of Literature

et al. 2022

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“…Classification of the antibacterial additives discussed in the review is shown in Figure 2. Of the 31 papers included, 11 [31,32,36,37,38,39,40,41,42,43,44] evaluated the effect of antiseptic additives, including natural agents (plant extracts) [42,43], two publications tested calcium hydroxide as an additive [45,46], 5 [23,24,25,28,47], and one [48] evaluated the effects of antibiotic and antifungal additives, respectively. Nanoparticles and/or nanoparticles functionalised with antimicrobial agents were studied in 12 papers [21,49,50,51,52,53,54,55,56,57,58,59].…”

Section: Reviewmentioning

confidence: 99%

“…Nanoparticles and/or nanoparticles functionalised with antimicrobial agents were studied in 12 papers [21,49,50,51,52,53,54,55,56,57,58,59]. The epoxy resin-based sealers used in the studies were AH Plus™ (Dentsply DeTrey, Konstanz, Germany) [23,24,25,31,32,38,39,40,41,42,43,45,46,47,48,49,50,51,52,53,54,56,57,58,59], AH 26™ (Dentsply DeTrey, Konstanz, Germany) [24,28,57], Sealer 26™ (Dentsply, Indústria e Comércio Ltda., Petrópolis, RJ, Brazil [48,50,51,52], Dentsply, Maillefer Instruments SA, Ballaigues, Switzerland [44]), ThermaSeal Plus™ (Dentsply Tulsa Dental, Tulsa, OK, USA) [21], MM-Seal ™ (MicroMega, Besançon, France) [36], BJM Root Canal Sealer™ (B.J.M. Laboratories, Or-Yehuda, Israel) [36,37], and RCS™ (B.J.M.…”

Section: Reviewmentioning

confidence: 99%

“…Saha et al [43] mixed three herbal extracts— Glycyrrhiza glabra (Licorice), Tinospora cordifolia (Guduchi), Mimusops elengi (Bakul)—with AH Plus™ and compared zones of inhibition in ADT against five aerobes and facultative anaerobes ( Staphilococcus aureus, Streptococcus ß haemolyticus , Enterococcus faecalis , Escherichia coli , Pseudomonas aeruginoca ) and two obligate anaerobes ( Peptostreptococcus spp., Bacteroides fragilis ). Licorice addition showed the largest zones of inhibition compared with the other two substances.…”

Section: Review Of Antimicrobial Effectsmentioning

confidence: 99%

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Antibacterial Additives in Epoxy Resin-Based Root Canal Sealers: A Focused Review

et al. 2019

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Dental materials used in root canal treatment have undergone substantial improvements over the past decade. However, one area that still remains to be addressed is the ability of root canal fillings to effectively entomb, kill bacteria, and prevent the formation of a biofilm, all of which will prevent reinfection of the root canal system. Thus far, no published review has analysed the literature on antimicrobial additives to root canal sealers and their influence on physicochemical properties. The aim of this paper was to systematically review the current literature on antimicrobial additives in root canal sealers, their anti-fouling effects, and influence on physicochemical properties. A systematic search was performed in two databases (PubMed and Scopus) to identify studies that investigated the effect of antimicrobial additives in epoxy resin-based root canal sealers. The nature of additives, their antimicrobial effects, methods of antimicrobial testing are critically discussed. The effects on sealer properties have also been reviewed. A total of 31 research papers were reviewed in this work. A variety of antimicrobial agents have been evaluated as additives to epoxy resin-based sealers, including quaternary ammonium compounds, chlorhexidine, calcium hydroxide, iodoform, natural extracts, antibiotics, antifungal drugs, and antimicrobial agent-functionalised nanoparticles. Antimicrobial additives generally improved the antimicrobial effect of epoxy resin-based sealers mainly without deteriorating the physicochemical properties, which mostly remained in accordance with ISO and ANSI/ADA specifications.

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“…Failure of endodontic treatment is closely associated with a bacterial infection. Therefore, the primary goal of endodontic therapy is the elimination of microorganism and their products inside the root canal system (1,2). Unfortunately, there are various bacterial species inside the root canal system, Enterococcus faecalis (E. faecalis) has been detected commonly in peri apical lesions on the other hand Staphylococcus aureus (S. aureus) has been detected in early diagnosis of root canal infection (3).…”

Section: Introductionmentioning

confidence: 99%

In vitro evaluation of the antibacterial effects of MTA- Fillapex and BIO-C® sealer at different time intervals

Saya Hadi Raouf,

Diyar Khalid Bakr,

Urfa Muneer Ahmed

et al. 2023

Cell Mol Biol (Noisy-le-grand)

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Influence of plant extracts mixed with endodontic sealers on the growth of oral pathogens in root canal: An in vitro study

Cited by 16 publications

References 0 publications

Herbal Medications in Endodontics and Its Application—A Review of Literature

Herbal Medications in Endodontics and Its Application—A Review of Literature

Antibacterial Additives in Epoxy Resin-Based Root Canal Sealers: A Focused Review

In vitro evaluation of the antibacterial effects of MTA- Fillapex and BIO-C® sealer at different time intervals

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