Influence of physical exercises on salivary immunoglobulin A (sIgA) concentration in athletes: a systematic review with meta-analysis

Castilho, Thuanny; Guimarães, Ludmila Silva; Póvoa, Helvécio Cardoso Corrêa; Antunes, Leonardo Santos; Antunes, Lívia Azeredo Alves

doi:10.1007/s11332-021-00870-4

Cited by 3 publications

(4 citation statements)

References 35 publications

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“…Studies have reported varying effects of exercise on the IgA level. A meta-analysis conducted in 2021 indicated that physical exercise resulted in a change in the salivary IgA level in athletes; however, this study had risk of bias and very low certainty of the evidence [76].…”

Section: Salivary Igamentioning

confidence: 85%

Effects of Probiotic Supplementation on Immune and Inflammatory Markers in Athletes: A Meta-Analysis of Randomized Clinical Trials

et al. 2022

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Background and Objectives: Probiotic supplementation can prevent and alleviate gastrointestinal and respiratory tract infections in healthy individuals. Markers released from the site of inflammation are involved in the response to infection or tissue injury. Therefore, we measured the pre-exercise and postexercise levels of inflammation-related markers—tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-8, IL-10, interferon (IFN)-γ, salivary immunoglobulin A (IgA), IL-1β, IL-2, IL-4, and C-reactive protein (CRP)—in probiotic versus placebo groups to investigate the effects of probiotics on these markers in athletes. Probiotics contained multiple species (e.g., Bacillus subtilis, Bifidobacterium bifidum, etc.). Materials and Methods: We performed a systematic search for studies published until May 2022 and included nine randomized clinical trials. Reporting followed the Preferred Reporting Items for Systematic Reviews and Meta-analyses guideline. Fixed-effects meta-analyses and sensitivity analyses were performed. Subgroup analyses were conducted on the basis of the period of probiotic intervention and timing of postassessment blood sampling. Results: The levels of IFN-γ and salivary IgA exhibited a significant positive change, whereas those of TNF-α and IL-10 demonstrated a negative change in the probiotic group. The subgroup analysis revealed that the probiotic group exhibited significant negative changes in TNF-α and IL-10 levels in the shorter intervention period. For the subgroup based on the timing of postassessment blood sampling, the subgroup whose blood sample collection was delayed to at least the next day of exercise exhibited significant negative changes in their TNF-α and IL-10 levels. The subgroups whose blood samples were collected immediately after exercise demonstrated negative changes in their TNF-α, IL-8, and IL-10 levels. Conclusions: Probiotic supplementation resulted in significant positive changes in the IFN-γ and salivary IgA levels and negative changes in the IL-10 and TNF-α levels. No significant changes in the IL-1β, IL-2, IL-4, IL-6, IL-8, or CRP levels were observed after probiotic use in athletes.

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Section: Salivary Igamentioning

confidence: 85%

Effects of Probiotic Supplementation on Immune and Inflammatory Markers in Athletes: A Meta-Analysis of Randomized Clinical Trials

et al. 2022

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“…Appart of serum IgA, several studies reported a significant change in salivary IgA as a consequences of intense physical exercise (see e.g. Nieman et al 2002, Castilho et al 2022. The relation, between serum/salivary IgA and coping with extreme Antarcic environment is, however, still poorly understood.…”

Section: Resultsmentioning

confidence: 99%

Changes in immunological characteristics of summer crew during a short term expedition to Antarctica

Žákovská

2023

Czech Polar Rep.

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The aim of this study was to examine the effect of extreme climatic conditions and isolation on levels of pre-selected immunological parameters in humans. This article describes changes in immunological parameters measured in members of the 9th Czech Antarctic Scientific Expedition during their field work in Antarctica in summer time. The total of 15 sera samples were collected in the morning shortly before the expedition, the second collection was proved in the middle and the third in the end of stay at the Czech Polar station (Mendel station). The statistically significant difference appeared in eight of 11 parameters, from which the value of C3, C4, IgA, and number of monocytes decreased; level of IgG and number of non segmented neutrophils increased. The difference was showed also in the middle of stay, when the level of IgM, number of neutrophils and lymphocytes in the first part of stay decreased, in the second increased. The way of life in the station, physical performance and extreme climatic condition, probably positively affected the results of some studied immunological parameters.

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“…Secretary immunoglobulin A (SIgA) is an antibody involved in the immune function of the mucous membranes. A recent systematic review concluded that physical exercise had no clear effect on SIgA 19 . Furthermore, cold exercise did not affect SIgA 20–22 ; however, mental stress can increase SIgA 23 .…”

Section: Introductionmentioning

confidence: 99%

“…A recent systematic review concluded that physical exercise had no clear effect on SIgA. 19 Furthermore, cold exercise did not affect SIgA [20][21][22] ; however, mental stress can increase SIgA. 23 Hence, curling matches that can increase mental stress, as mentioned above, might increase SIgA, although this requires direct investigation.…”

mentioning

confidence: 99%

Thermal stress, hydration, and salivary and respiratory stress markers in curling players performing a match in the cold

Tanabe

Suzuki

Kojima

et al. 2023

Scandinavian Med Sci Sports

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Curling is a winter Olympic sport and a target-based team game that is played in a cold environment (5-10°C). Players release a stone into a target area on the ice called a house, and two teammates sweep the surface of the ice to guide the delivered stone toward the target, competing for points determined by which team can place more stones. Some studies have assessed curling athletes by characterizing heart rate response 1 and muscle activity 2

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Influence of physical exercises on salivary immunoglobulin A (sIgA) concentration in athletes: a systematic review with meta-analysis

Cited by 3 publications

References 35 publications

Effects of Probiotic Supplementation on Immune and Inflammatory Markers in Athletes: A Meta-Analysis of Randomized Clinical Trials

Effects of Probiotic Supplementation on Immune and Inflammatory Markers in Athletes: A Meta-Analysis of Randomized Clinical Trials

Changes in immunological characteristics of summer crew during a short term expedition to Antarctica

Thermal stress, hydration, and salivary and respiratory stress markers in curling players performing a match in the cold

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