Influence of Photoperiod on Reproductive Development in the Golden Hamster

Darrow, Janet M.; Davis, Fred C.; Elliott, Jeffrey A.; Stetson, Milton H.; Turek, Fred W.; Menaker, Michael

doi:10.1095/biolreprod22.3.443

Cited by 54 publications

(30 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In that study, although body weight was not affected by photoperiod, P. campbelli testes weight and uterine weight at 35 days were reduced under 8 h light:16 h darkness relative to 16 h light:8 h darkness (Ebling 1994). Therefore, the developmental pattern for reproductive tissues in P. campbelli is not the same as the 'develop and then regress' pattern described for golden hamsters (Darrow et al 1980). Thus, the developmental trajectories for reproduction in P. campbelli did not follow established patterns for P. sungorus or the golden hamster.…”

Section: Discussionmentioning

confidence: 69%

“…This latter pattern is typical of the responses of juvenile golden hamster (M. auratus) to gestation in long days, and Photoperiod and hamster development rearing in short days (Gaston & Menaker 1967, Darrow et al 1980. The earlier study comparing these two species of Phodopus, however, also included measures of reproductive tissues at 35 days in addition to measures at 70 days (Ebling 1994).…”

Section: Discussionmentioning

confidence: 84%

“…In contrast, the golden hamster (Mesocricetus auratus) exhibits a robust reproductive response to short photoperiod as an adult. In juveniles, the growth, development, and the timing of puberty are not affected by rearing in short photoperiod or total darkness (Darrow et al 1980).…”

Section: Introductionmentioning

confidence: 94%

See 2 more Smart Citations

Phodopus campbelli detect reduced photoperiod during development but, unlike Phodopus sungorus, retain functional reproductive physiology

Timonin¹,

Place²,

Wanderi³

et al. 2006

Reproduction

View full text Add to dashboard Cite

Golden (Mesocricetus auratus) and Siberian (Phodopus sungorus) hamsters are widely used as animal models for seasonal reproduction; but M. auratus shows no developmental delay in short days until after sexual maturity, whereas P. sungorus juveniles delay development in short days. As the photoperiodic response of Phodopus campbelli is not well established, litters of the two Phodopus species were gestated and reared under long days (14 h light:10 h darkness) or short days (10 h light:14 h darkness) until 70 days of age. As expected, under short photoperiod P. sungorus showed reduced body, testes, epididymides, uterus, and ovary weight; antral follicles and corpora lutea were absent and vaginae remained closed. Animals moulted to winter pelage, and low concentrations of each of leptin, testosterone, and prolactin were present in male serum. Phodopus campbelli juveniles also responded to the short photoperiod as measured by reduced body, testes, epididymides, and ovary weight. The summer pelage persisted. However, both sexes of P. campbelli developed functional reproduction under 10 h light:14 h darkness. All females had a patent vagina by 10 weeks; ovaries contained antral follicles and corpora lutea, and uteri were not reduced in weight. In males, the concentrations of testosterone, leptin, and prolactin were not reduced by short photoperiod. Developmental patterns in the three species of hamster, therefore, differ and are not predicted by relatedness or latitude of origin. Other ecological traits, such as predictability of summer rainfall, ambient temperature, and differential responses to social cues might be important.

show abstract

Section: Discussionmentioning

confidence: 69%

Section: Discussionmentioning

confidence: 84%

See 1 more Smart Citation

Phodopus campbelli detect reduced photoperiod during development but, unlike Phodopus sungorus, retain functional reproductive physiology

Timonin¹,

Place²,

Wanderi³

et al. 2006

Reproduction

View full text Add to dashboard Cite

show abstract

“…Previous studies have demonstrated that FSH can induce follicular growth in the virtual absence of LH; however, estrogen production is severely impaired (McNatty et al 1979, Schoot et al 1992, Shemesh 2001. Given that serum LH levels are much lower in SD than in LD female hamsters (Darrow et al 1980, Dodge & Badura 2002, it is possible that FSH-dependent estrogen production by granulosa cells is substantially reduced due to a decrease in LH-induced androgen precursor production by theca cells. The observed lack of effect of rhFSH on uterine mass and vaginal patency, which are largely estrogen-dependent traits (Odum et al 1997, van Meeuwen et al 2007, Suzuki et al 2007, Baranda-Avila et al 2009), supports these conclusions.…”

Section: Long-term Rhfsh Supplementation In Sdsmentioning

confidence: 99%

Photoperiod-gonadotropin mismatches induced by treatment with acyline or FSH in Siberian hamsters: impacts on ovarian structure and function

et al. 2012

View full text Add to dashboard Cite

Many seasonal breeders time their reproductive efforts to specific times of the year to ensure adequate resources for the production and care of young. For long-day (LD) breeders, females born before the summer solstice (LDs) reach sexual maturity quickly and often breed that same year, whereas females born after the summer solstice (short days (SDs)) may delay reproductive development to the following spring when environmental conditions are favorable for reproduction. In Siberian hamsters, development in SD is associated with structural and functional differences in the ovary compared with females held in LD, including a greater number of primordial follicles and an abundance of hypertrophied granulosa cells (HGCs), which are immunoreactive for anti-Mü llerian hormone. The goal of this study was to determine whether SD-induced gonadotropin suppression is responsible for these phenotypic differences. Gonadotropin levels were suppressed in LD hamsters using the GNRH antagonist acyline. Conversely, to determine whether the SD ovarian phenotype is completely reversed by gonadotropin stimulation, recombinant human FSH (rhFSH) was administered. Our treatments were successful in mimicking FSH concentrations of the opposite photoperiod, but they did not produce a comparable change in the ovarian phenotype. Most notable was the lack of HGCs in the ovaries of acyline-treated LD females. Similarly, HGCs were maintained in the ovaries of SD females treated with rhFSH. Our data suggest that gonadotropins alone do not account for the SD ovarian phenotype. Future studies will determine whether SD-induced changes in other factors underlie these phenotypic changes.

show abstract

“…The Syrian hamster (Mesocricetus auratus) undergoes a seasonal fluctuation in reproductive function following a photoperiodic-independent reproductive maturation (Darrow et al, 1980;Elliott and Goldman, 1981;Smith et al, 1982). Some species, unlike the Syrian hamster, are also dependent on the photoperiod for their reproductive maturation.…”

Section: Introductionmentioning

confidence: 99%

The effects of feedback lighting on the circadian rhythm of locomotor activity and the reproductive maturation of the male Djungarian Hamster(Phodopus sungorus)†

Ferraro

1988

Journal of Interdisiplinary Cycle Research

View full text Add to dashboard Cite

The non-parametric model of entrainment suggests that brief pulses of light, delivered between dusk and dawn can simulate the phasing effects of full photoperiods or even constant light (LL). Feedback lighting (LDFB) is a lighting condition where individual animals, otherwise in constant darkness (DD), are exposed to light in response to a monitored behavior. The specific purpose of this type of illumination is to expose the circadian cycle to light only during the subjective night. LDFB has been used to support this hypothesis in several species of nocturnal rodents and one species of diurnal primate by producing similar free-running periods in LDFB as in LL. This lighting condition has also been used to test the hypothesis that exposing the subjective night to even short duration light pulses will maintain reproductive function in long day breeders. In the Syrian hamster (Mesocricetus auratus), however, LDFB is not as photostimulatory as LL despite extensive light exposure during the subjective night. In the experiments presented here, a group of immature male Djungarian hamsters (Phodopus sungorus) were placed in individual light-tight sound attenuated chambers where they had free access to food, water and an activity wheel. The animals were exposed to one of four lighting conditions [DD, LL, LDFB or a neighbor control of feedback lighting (LDFB NC)] for approximately 30 days shortly after weaning. LDFB NC is a lighting condition where a neighbor control hamster receives the identical lighting regime as a paired animal exposing itself to LDFB, yet the neighbor has no control over it. A fifth group was exposed to a light-dark cycle of 16 hours of light and 8 hours of dark (LD16:8). This group was housed in cages in a colony room and did not have access to a running wheel. The free-running periods of the locomotor activity rhythms for hamsters exposed to LDFB and LL were not similar, unlike the results for rats, Syrian hamsters, mice, monkeys and even mature Djungarian hamsters. Immature hamsters exposed to DD and LDFB NC developed more slowly than animals exposed to LL or LD16:8, while hamsters in LDFB developed at an intermediate rate. Thus, it appears that LDFB, although capable of inducing reproductive function in immature Djungarian hamsters, is not as photostimulatory as may have been expected from current photoperiodic models, despite substantial light exposure during the subjective night. Furthermore, this data may suggest that the circadian system of 18-48 day old Djungarian hamsters are still undergoing organizational maturation.

show abstract

Influence of Photoperiod on Reproductive Development in the Golden Hamster

Cited by 54 publications

References 22 publications

Phodopus campbelli detect reduced photoperiod during development but, unlike Phodopus sungorus, retain functional reproductive physiology

Phodopus campbelli detect reduced photoperiod during development but, unlike Phodopus sungorus, retain functional reproductive physiology

Photoperiod-gonadotropin mismatches induced by treatment with acyline or FSH in Siberian hamsters: impacts on ovarian structure and function

The effects of feedback lighting on the circadian rhythm of locomotor activity and the reproductive maturation of the male Djungarian Hamster(Phodopus sungorus)†

Contact Info

Product

Resources

About