Influence of parental history of hypertension on blood pressure

Abstract

Aim: To assess the effect of parental history of hypertension on blood pressure in representative samples from three French populations (MONICA centres of Lille, Strasbourg, Toulouse). Methods: We screened 1660 males and 1635 females, aged 35-64 years. Subjects were defined as hypertensive if systolic blood pressure у160 mm Hg or diastolic blood pressure у95 mm Hg or if they were treated by antihypertensive drugs. Four groups of parental history were determined: no parental history; at least one parent hypertensive before 60 years; hypertension was diagnosed after 60; and hypertension with unknown age of discovery. A logistic regression model was used separately for each sex.

Prevalence and Determinants of Prehypertension in a Japanese General Population: The Jichi Medical School Cohort Study

“…Hahn et al reported that parental history was related to higher BP in females, but not in males, while Goldstein et al reported that elevated SBP and DBP measured by ambulatory monitoring was related to a family history of HT in both parents in males, but there was no association in females (21,22). It has also been reported that females tend to have a better knowledge of their own and their family's health status than males (23). Our findings indicate that females with a family history of HT were more likely to have high BP than males with a family history of HT.…”

“…Additionally, when we analyzed determinants of pre-HT by dividing females into two groups, i.e., above or below the age of 50 years, determinants of pre-HT in the older females were BMI≥ 23 Determinants of HT (vs. NT) in males and females are shown in Table 3. Overweight and obesity were the strongest determinants of HT in comparison with NT.…”

How family history and risk factors for hypertension relate to ambulatory blood pressure in healthy adults

“…A parent was identified as hypertensive if he/she was diagnosed with hypertension before the age of 60 and hypertension was present for at least 1 year. This procedure was followed because hypertension diagnosed in a parent after 60 years of age was not found to be a significant risk factor for the development of hypertension in offspring [17]. Parents had to have had a physical examination within the last year, knowledge of BP level, and, if pertinent, information on current antihypertensive status and medications.…”

Central blood pressure parameters in young adults with and without parental history of hypertension

“…Also, this relationship depended on the age at which hypertension had been diagnosed in parents. 7 In the current study, multivariate analysis did not reveal any significant main effects of gender and parental history of hypertension alone and also no statistically significant interaction effect between the two.…”