This study aimed to investigate the effect of moral disengagement (professor and student), perceived opportunity, culture (collectivism-individualism), and religiosity (organizational religiosity, non-organizational religiosity, and intrinsic religiosity) on academic dishonesty in college student. The data was collected from 515 undergraduate students of the state college in Java, by nonprobability sampling technique. The data analysis used multivariate regression analysis. The result indicated that the model was saturated. Moral disengagement student predicted all of the dependent variables. Further, moral disengagement professor only significantly predicted cheating and facilitating academic dishonesty. Meanwhile perceived opportunity and collectivism predicted cheating, and non-organizational religiosity predicted fabrication. Future research is needed to determine the other factors which influence academic dishonesty and use other a regression model.