Influence of Narrow Band Imaging (NBI) Videobronchoscopy on the Assessment of Central Lung Cancer Extension and Therapeutic Decision

Narrow-band imaging bronchoscopy in the detection of premalignant airway lesions: a meta-analysis of diagnostic test accuracy

“…The studies by Shibuya and colleagues [Shibuya et al 2010[Shibuya et al , 2003] were also excluded as no data on sensitivity or specificity were obtainable from these studies. Therefore, for our metaanalyses of diagnostic accuracy, a total of eight studies [Zaric et al 2009[Zaric et al , 2012[Zaric et al , 2013b[Zaric et al , 2013cHerth et al 2009;Bojan et al 2009;Vincent et al 2007;Chen et al 2013] for NBI were included and analyzed. Four of these studies [Chen et al 2013;Herth et al 2009;Zaric et al 2012Zaric et al , 2013c were analyzed to determine the diagnostic performance of combined NBI and AFI.…”

“…1 study by Yamada et al [2011] 2 studies by Shibuya et al [2002Shibuya et al [ , 2010 8 studies included in the meta-analysis: Zaric et al [2009Zaric et al [ , 2012Zaric et al [ , 2013bZaric et al [ , 2013c, Herth et al [2009], Bojan et al [2009], Vincent et al [2007], Chen et al [2013] MeSH words used: Test performance: meta-analysis Sensitivity and specificity. Analysis of data from eight studies on NBI [Zaric et al 2009[Zaric et al , 2012[Zaric et al , 2013b[Zaric et al , 2013cHerth et al 2009;Bojan et al 2009;Vincent et al 2007;Chen et al 2013] showed a pooled sensitivity of 0.80 [95% confidence interval (CI): 0.77-0.83], I 2 93 and a pooled specificity of 0.84 (95% CI: 0.81-0.86), I 2 1, respectively, as shown in Figure 2. From the four studies [Chen et al 2013;Herth et al 2009;Zaric et al 2012Zaric et al , 2013c reporting a combination of AFI and NBI procedures, a pooled sensitivity of 0.86 (95% CI: 0.82-0.89), I 2 89.1 and a pooled specificity of 0.75 (95% CI: 0.71-0.79), I 2 96.3, respectively, were obtained, as shown in Figure 3.…”

“…The DOR from data on NBI [Bojan et al 2009;Chen et al 2013;Vincent et al 2007;Zaric et al 2009Zaric et al , 2012Zaric et al , 2013bZaric et al , 2013c was 31.49 (95% CI: 12.17-81.45). The DOR for procedures where both NBI and AFI were combined [Chen et al 2013;Herth et al 2009;Zaric et al 2012Zaric et al , 2013c was 27.96 (95% CI: 3.04-257.21).…”

“…A blue narrow band, wavelength ranging from 390 to 445 nm, is absorbed by surface mucosal layer capillaries and a green narrow band, wavelength between 530 and 550 nm, is absorbed by the deeper submucosal thick blood vessels [Herth et al 2010]. Recent studies on NBI have shown higher if not equal sensitivity compared with AFI in the detection of premalignant airway lesions [Bojan et al 2009;Zaric et al 2012]. Specificity has also been shown to be higher in NBI than AFI [Chen et al 2013;Herth et al 2009].…”

GASTRO 2009 Bericht: Perspektiven der Endoskopie

“…NBI ist eine kontrastverstärkende Technik, die in zahlreichen Studien für verschiedene Indikationen eingesetzt wird, überwiegend im Gastrointestinaltrakt [56][57][58][59][60][61][62][63][64][65][66], für ampulläre und pankreatikobilläre Erkrankungen [66][67][68][69], und aktuell auch in anderen Systemen [66,[70][71][72][73] [77]. Ähnliche Resultate erzielte eine andere Untersuchung an 20 Patienten mit oberflächlichen Plattenepithelkarzinomen des Ösophagus mit der Schlussfolgerung, dass die Anwendung von M-NBI die Genauigkeit der Standardendoskopie von 80 % auf 85 % erhöht [78].…”