Abstract:IntroductionControlled trials in children and adolescents have shown that, small-dose naloxone infusions (0.25µg/kg/hour) can significantly reduce opioid induced side effects without affecting opioid-induced analgesia.
Material and methods84 elective thoracotomy patients having combined thoracic epidural and general anesthesia for thoracotomy surgeries were randomly assigned to one of the two study groups. All patients of Group A (n=42) received continuous intravenous infusion of naloxone at a calculated dose … Show more
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