Influence of Mydriatic Eye Drops on Wavefront Sensing With the Zywave Aberrometer

Taneri, Suphi; Oehler, Saskia; Azar, Dimitri T.

doi:10.3928/1081597x-20110317-01

Cited by 21 publications

(4 citation statements)

References 17 publications

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“…The conclusion of this paper is compatible with previous studies and theories [10]. It has to be mentioned that there are also very few cases with a small amount (-0.25 D) of adverse deviation, which may be due to: (1) Signi cant changes in high-order aberrations of eyes after pupil dilation will affect the measurement of diopter to vary degrees [11,12]. (2)Adolescents have extremely strong accommodation function, so the optometry results under the tiny pupil may not be reliable.…”

Section: Discussionsupporting

confidence: 90%

A Study Based on CASIA2: What the Subtle Changes Has Taken Place in the Shape of the Crystalline Lens After Cycloplegia?

Dai

Meng

et al. 2021

Preprint

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Background: To evaluate the shape of the crystalline lens biometry and the diopter before and after cycloplegia using the CASIA2 swept-source (SS) optical coherence tomography (OCT) system on the anterior segment.Methods: This is a retrospective study. Children and adolescents (26 males and 29 females, aged 4–21 years) with simple ametropia were selected for optometry and CASIA2 imaging at 2 separate visits before and after cycloplegia. Diopter is derived from the spherical power (S) obtained by optometry. The Biometric parameters of the crystalline lens, including anterior chamber depth (ACD), anterior and posterior curvature of the lens (ACL and PCL), lens thickness (LTH), lens decentration(LD), lens tilt(LT), and the equivalent diameter of the lens (LED), were measured by CASIA2. The differences of these parameters before and after cycloplegia were compared, and the relationship between them was analyzed.Results: Fifty-five participants (106 eyes) were initially enrolled. The differences were statistically significant(P<0.05) in S (t=-7.026, P=0.000), ACD (t=-8.796, P=0.000), ACL (t=-13.263, P=0.000) and LTH（t=7.363, P=0.000）before and after cycloplegia. The change of PCL (t=1.557,P=0.122), LD (t=0.876, P=0.383), LT (t=0.440, P=0.661) and LED（t=-0.351, P=0.726） was not statistically significant (P>0.05). There was a significant (P<0.05) correlation between the change in S and ACL(r=0.466, P=0.000),LTH (r=-0.592, P=0.000),and LED (r=0.223, P=0.021) but not between the PCL(r=0.19, P=0.051), LD (r=-0.048, P=0.0628) and LT (r=-0.022, P=0.822). Furthermore, the change of ACD is closely related to the change of crystal morphology. However, in children and adolescents, we found that the change of crystal morphology will not have anything to do with age.Conclusion: The morphological changes of the lens before and after cycloplegia are mainly the ACL and LTH, but there is no difference in the PCL, LD, LT, and LED. In the adolescent population, the change of S is related to the change of ACL, LED and LTH. However, age gets nothing to do with the shape of the crystalline lens. For different refractive states (myopia, hyperopia, emmetropia), whether groups of different ages can reach the same conclusion needs further research.

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Section: Discussionsupporting

confidence: 90%

A Study Based on CASIA2: What the Subtle Changes Has Taken Place in the Shape of the Crystalline Lens After Cycloplegia?

Dai

Meng

et al. 2021

Preprint

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“…This study has several limitations. First, concerning measurement of wavefront and HOAs, the constants of Zernike polynomials vary with the size of the pupils, making pupil size an important factor [ 22 , 23 ]. However, in the present study, the subjects were children aged between 9 and 15 years, with relatively small-sized pupils.…”

Section: Discussionmentioning

confidence: 99%

Serially Checked Spherical Aberration Can Evaluate the Anti-Myopia Effect of Orthokeratology Lens in Children

Hahn

Lee

Lee³

et al. 2022

JPM

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We aimed to investigate the changes in higher-order aberrations (HOAs) after wearing orthokeratology (OK) lenses in myopic patients. The study included 15 eyes from ten myopic patients, whose refractive error was myopia less than −4.5 diopters (D) and astigmatism less than 1.5 D. Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA) were measured, and Zywave® aberrometry was performed at baseline and 1, 3, and 6 months following OK lens wear. The mean age was 11.5 years (range: 9–15 years). There was a significant improvement in UCVA (p ≤ 0.001) and a decrease in the spherical equivalent measured with auto-refraction at 6 months (p ≤ 0.001). Total HOAs significantly increased after OK lens wear (p ≤ 0.001), with spherical aberration increasing approximately 3.9-fold (p = 0.05). Spherical aberration demonstrated statistically significant positive correlations with the change in spherical equivalent at 3 and 6 months (p = 0.007 and 0.003, respectively). After wearing properly prescribed OK lens, all subjects had significantly improved UCVA and decreased myopic spherical equivalent, with increased total HOAs and positive spherical aberration at 1 month, and the changes were maintained at 6 months. Serially checked spherical aberration could evaluate the anti-myopia effect of the orthokeratology lens in children.

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“…Taneri et al 43 investigated the influence of mydriatic eye drops on aberrometry measurements taken with the Zywave™ aberrometer in terms of the predicted phoropter refraction (PPR) and HOAs. A mydriatic dilated group of eyes were compared with a group of non-dilated eyes.…”

Section: Mydriatic Dropsmentioning

confidence: 99%

Higher order aberrations of the eye: Part two

Oberholzer¹,

Gillan²,

Rubin³

2016

African Vision and Eye Health

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This article is the second in a series of two articles, which provides a discussion of the factors that may possibly contribute to variable results when wavefront aberrations of the human eye are measured. Some of the factors discussed in this article are the influences that refractive errors (specifically myopia and astigmatism), pupil diameter, accommodation of the crystalline lens, age, mydiatric drops and the integrity of the tear film may have on these wavefront measurements. The first article in the series explained the general principles of higher order aberrations (HOAs), as well as HOAs of importance in the eye and the measuring apparatus used to measure HOAs of the eye.Keywords: wavefront aberrations; aberrometry

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Influence of Mydriatic Eye Drops on Wavefront Sensing With the Zywave Aberrometer

Abstract: The cycloplegic effect of mydriatic eye drops should be taken into account when interpreting aberration measurements and planning a wavefront-guided ablation. Ideally, the use of mydriatic eye drops should be avoided to minimize refractive surprises.

Cited by 21 publications

References 17 publications

A Study Based on CASIA2: What the Subtle Changes Has Taken Place in the Shape of the Crystalline Lens After Cycloplegia?

A Study Based on CASIA2: What the Subtle Changes Has Taken Place in the Shape of the Crystalline Lens After Cycloplegia?

Serially Checked Spherical Aberration Can Evaluate the Anti-Myopia Effect of Orthokeratology Lens in Children

Higher order aberrations of the eye: Part two

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