Influence of Mycoremediation and Selected Surfactants on Growth Performance of Fluted Pumpkin In Crude Oil Impacted Soil and the Nephrotoxic Effects of Leaves Aqueous Extract on Wistar Rats

Nwauche, K. T.; Anacletus, F. C.; Berezi, E. P.

doi:10.9734/ijbcrr/2018/42190

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…Slides were observed under a light microscope after being stained with hematoxylin and eosin (H&E) dyes and mounted. 22 Capture and scoring for morphological changes were done by a pathologist blind to the treatments at the Pathology Unit, University of Port Harcourt Teaching Hospital.…”

Section: Qualitative Analysis Of Phytochemicalsmentioning

confidence: 99%

Hypolipidemic Potentials of Aqueous Leaf Extract of Cape Fig (Ficus capensis thunb) in High Fat Diet-Induced Hyperlipidemic Rats

2021

TJNPR

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Nature has been a source of medicinal agents for thousands of years and an impressive number of modern drugs have been isolated from natural sources, mainly based on their use in traditional medicines. The study was carried out to evaluate the hypolipidemic potentials of Ficus capensis thunb in high fat diet-induced hyperlipidemic rats. Twenty-five (25) Wistar rats were used for this study and were grouped into five groups consisting of five animals. Hyperlipidemia was induced by feeding the rats with high fat diet for a period of four (4) weeks. The results from the phytochemical analysis of the plant revealed the presence of tannins, saponins, protein, xanthroprotein, anthraquinones, alkaloids, phenolic compound, flavonoids and cardiac glycosides. After a period of four weeks of feeding, hyperlipidemia was established judging from significant increase (p˂0.05) in serum levels of TC-C, LDL-C and TG with a concomitant decrease in serum HDL levels as compared to normal rats. Treatment with aqueous leaf extract of Ficus capensis at a doses of 200, 400 mg/kg b.w and also with simvastatin at a dose of 10 mg/kg b.w orally for 28 day significantly (p˂0.05) decreased the serum levels of TC, TG and LDL accompanied by an increase in serum level of HDL as compared with those of the hyperlipidemic group. The liver tissues of hyperlipidemic group were characterized by fat accumulation, vascular congestion, cords disorder, and infiltration of inflammatory cells. Aqueous leaf extract of Ficus capensis mitigated both the elevated serum lipid and histological abnormalities.

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Section: Qualitative Analysis Of Phytochemicalsmentioning

confidence: 99%

Hypolipidemic Potentials of Aqueous Leaf Extract of Cape Fig (Ficus capensis thunb) in High Fat Diet-Induced Hyperlipidemic Rats

2021

TJNPR

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“…Also, fishes are considered as early warning for reduction in environmental quality, and also specific measures of the existence of harmful, cancer causing and mutagenic compounds in biological materials [1]. The exploration of petroleum products has rendered agricultural lands less productive and the creeks and the aquatic lives have become more or less dead [2]. Liver and gills as the fish's main organs for metabolism and respiration are targeted by contaminants for accumulation as reported by many authors concerning damage to the structure of organs and tissues related to the exposure of fish to petroleum derivatives [3].…”

Section: Introductionmentioning

confidence: 99%

Comparative Assessment of Some Biochemical Indices in Catfish from Rivers, Swamp and Commercial Fish Ponds in Oil and Non-Oil Polluted Areas in Rivers and Anambra States

Fc¹

2019

IJBP

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This study was carried out to comparatively assess some biochemical indices in eighteen catfish harvested from rivers, swamp and commercial fish ponds in oil polluted and non-oil polluted areas. Three fishes were collected from each of the following sites; Akaraolu swamps in Ahoada East LGA (AR), a commercial fish pond within the area (AP), The New Calabar River in Ikwerre LGA (BR), a fish pond within the area (BP), Omambala River, Anambra East LGA (CR), a fish pond in Awka, Anambra state (CP), six groups in all. Analysis was done following standard procedures for the biochemical assays carried out. On analysis, the ALP and ALT activities (33.93±2.37 and 44.33±2.96 respectively) from AR were significantly (p<0.05) different from BR (17.00±0.58 and 35.00±5.69 respectively) and CR (22.00±2.31 and 30.67±2.60 respectively). The AST activity from AR (68.67±0.88) was not significantly different from that of BR (69.00±1.73) but was significantly different from that of CR (70.33±4.33).Also, site AP (65.53±0.37, 73.00±2.08 and 50.00±1.15 respectively) were significantly higher than CP (42.00±2.89, 64.67±4.33 and 44.67±5.46 respectively) and BP (26.00±1.15 and 50.20±1.15 respectively). However, the AST activity of catfish from AP (73.00±2.08) was not significantly different from that in BP (73.67±1.86). The creatinine, urea, Na + and K + concentrations observed from AR and AP were significantly higher in comparison to other sites. There was a significantly increased GSH, Catalase, and MDA, and a lower SOD concentration for AR and AP in comparison to other sites. The results show a variation in biochemical indices in fishes from oil polluted sites when compared to non-oil polluted sites.

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Influence of Mycoremediation and Selected Surfactants on Growth Performance of Fluted Pumpkin In Crude Oil Impacted Soil and the Nephrotoxic Effects of Leaves Aqueous Extract on Wistar Rats

Cited by 2 publications

References 12 publications

Hypolipidemic Potentials of Aqueous Leaf Extract of Cape Fig (Ficus capensis thunb) in High Fat Diet-Induced Hyperlipidemic Rats

Hypolipidemic Potentials of Aqueous Leaf Extract of Cape Fig (Ficus capensis thunb) in High Fat Diet-Induced Hyperlipidemic Rats

Comparative Assessment of Some Biochemical Indices in Catfish from Rivers, Swamp and Commercial Fish Ponds in Oil and Non-Oil Polluted Areas in Rivers and Anambra States

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