Influence of Mixing Liquid on the Properties of Calcium Aluminate Cement

Morejón-Alonso, Loreley; Santos, Luís Alberto dos; Carrodeguas, Raúl García

doi:10.4028/www.scientific.net/kem.396-398.241

Cited by 3 publications

(2 citation statements)

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“…The first level of testing in the evaluation of biocompatibility of biomaterials is the determination of in vitro cytotoxicity. Although it is known that large amounts of aluminium ions could be toxic [39], the addition of CA to these formulations did not increase the toxicity of the composite, once the amount added does not produce a detectable release of Al 3+ ions to the medium [13]. The results of cell culture showed that composites containing CA are less cytotoxic and more compatible than pure -TCP-based cement.…”

Section: Discussionmentioning

confidence: 94%

“…The high water turnover gives the system a potentially high strength, several times that of normal CPCs. Moreover, CACs have good corrosion resistance in contact with body fluids and are biocompatible since the amount of Al ion leakage is very low [12,13]. In these materials, the main phase commonly used is monocalcium aluminate [CaAl 2 O 4 , CA] due to its optimal reaction rate compared with the other phases.…”

Section: Introductionmentioning

confidence: 99%

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Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

Morejón-Alonso¹,

Carrodeguas²,

Santos³

2012

JBiSE

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Calcium phosphate cements have received much attention in recent decades owing to their biocompatibility, <i>in situ</i> handling, and shaping abilities. However, their low initial mechanical strength is still a major limitation. On the other hand, calcium aluminate cements (CACs) set fast and have a high initial strength and good corrosion resistance in contact with body fluids, making them excellent dental restorative materials. Therefore, the chemical, mechanical and biological properties of new-TCP/CA cement after aging in simulated body fluid (SBF) were investigated. The results indicated that the composites have setting times not appropriated for immediate applications and have degradation rates higher than those of the traditional CPCs. Moreover, the compressive strength of composite was lower than 5MPa and did not increase with SBF immersion. However, the <i>α</i>-TCP/CA composites showed a higher bioactivity at early stages and were not only more biocompatible but also more noncytotoxic

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Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

Morejón-Alonso¹,

Carrodeguas²,

Santos³

2012

JBiSE

View full text Add to dashboard Cite

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Compositions of calcium aluminate cement containing gold and silver nanoparticles for biomaterial applications

et al. 2020

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Calcium aluminate cement-based blends for application to fill in bone defects

et al. 2020

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Introduction The need to treat bone defects is increasing dramatically as the population grows old. Calcium aluminate cement, CAC, has been applied to fill in bone defects. CAC has been used in orthopedics, as it can avoid some problems of commercial products, polymethylmethacrylate, PMMA, regarding its too low consistency and strong odor and exothermic reactions which can damage the surrounding tissue. Besides that, CAC can be molded in situ to provide intimate fitting to the defect rims. The injectability of cements is an important aspect when minimally invasive surgical techniques are used and for applications with limited accessibility and narrow cavities. Methods At present work, CAC was initially analyzed via zeta potential and viscosity when mixed with different dispersant additives. Then, CAC blends containing different materials, alumina, zirconia, zinc oxide, hydroxyapatite, tricalcium phosphate, chitosan, collagen, or zinc oxide-bismuth oxide, were evaluated regarding their injectability and by means of in vitro mineralization and ex vivo uniaxial cold crushing strength tests. The best injectability conditions, 76 wt% solids, hypodermic needle, were used for the ex vivo tests. In the latter, the compositions selected by in vitro tests were injected to repair 3-mm defects on mouse femurs cut into pieces of 10 mm, whereas collagen and PMMA were inserted with a spatula. After setting the materials for 24 h at 37°C in body fluid solution, the pieces were submitted to uniaxial cold crushing strength tests. Results The blends alumina, collagen, and chitosan resulted in greater reddish-stained areas indicating enhanced mineralized matrix formation for these groups, which also presented higher values of calcium deposits indicating a successful in vitro bonelike nodule formation. Conclusion The filling of defects with CACH and its blends increased the resistance of bones when compared to bones with the added defect, with lower effect verified in the presence of chitosan and collagen.

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Influence of Mixing Liquid on the Properties of Calcium Aluminate Cement

Cited by 3 publications

References 4 publications

Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

Development and characterization of α-tricalcium phosphate/monocalcium aluminate composite bone cement

Compositions of calcium aluminate cement containing gold and silver nanoparticles for biomaterial applications

Calcium aluminate cement-based blends for application to fill in bone defects

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