Influence of medical comorbidities, smoking, and alcohol on mycosis fungoides progression and mortality

Abstract

Influence of medical comorbidities, smoking, and alcohol on mycosis fungoides progression and mortality Dear Editor, Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma. Previous reports have described racial, demographic, and socioeconomic disparities in MF progression-free survival (PFS) 1,2 and found increased levels of homocysteine, high sensitivity C-reactive protein, low-density lipoprotein, and total cholesterol in MF patients compared to healthy controls, suggesting higher cardiovascular risk. 3 Moreover, significantly higher rates of congestive heart failure, hypertension, and hyperlipidemia have been observed in MF patients in comparison to the general population. 4 However, current studies have not examined whether these risk factors impact MF disease progression or death. Therefore, we examined the influence of cardiac, metabolic, hematologic, and auto-*P < 0.05. **P < 0.01. ***P < 0.001.