Influence of maternal nutrition on birth weight

Abstract

This paper discusses some conditions necessary to detect an effect of maternal nutrition on birth weight and the relative contribution of calories and protein to such an effect. The expected dose- and time-response relationships for nutritional interventions aimed at the improvement of birth weight are also discussed. There appears to be a minimal level of nutrients which must be available in order to obtain adequate birth weight. However, above this minimum level, pregnant women can adapt themselves to a wide variety of food intake, both in quantity and quality, without affecting birth weight. The relative contribution of calories and protein to an increase in birth weight depends on the limiting nutrients of the home diet in the population under study. Other factors like physical activity, prevalence of disease and magnitude of the maternal nutritional stores before pregnancy are also important determinants of the relative contribution of calories and protein to birth weight. The anticipated input of a nutritional intervention on birth weight should range between 25 and 84 g of birth weight/10,000 kcal ingested during pregnancy. This estimate was computed from analyses based on four sources of published data: weight gain during pregnancy, prepregnant weight, fetomaternal body composition, and food intake during pregnancy. The expected reduction in proportion of low birth weight (LBW less than 2.5 kg) babies following a nutritional intervention will depend not only on the estimated range of fetal weight increase but also on the total amount of supplemented calories ingested during pregnancy as well as on the existent proportion of low birth weight babies prior to the intervention. The offspring of women who have low prepregnant weight, poor diet, low level of replacement of the home diet by the supplement, low physical activity during pregnancy and good health status will show larger increase in birth weight per unit of supplemented calories. Finally, nutritional interventions during pregnancy as opposed to earlier in the life of the mother, should have the higher impact on birth weight. In consequence, interventions as of pregnancy are recommended.

Determinants of malnutrition among pregnant and lactating women under humanitarian setting in Ethiopia

“…Previous studies have established that malnourished pregnant women are at increased risk of having LBW infants [5,6]. The link between LBW and poor health and nutritional outcomes later in life is also well established, with several studies reporting the association of LBW with malnutrition, poor growth and development, and increased morbidity and mortality in children [7][8][9][10].…”

Early participation in prenatal food supplementation program ameliorates the negative association of food insecurity with quality of maternal-infant interaction

“…Food supplementation programs influence prenatal nutrition (38) and social conditions (54) and could thereby influence maternal-infant interaction through both biological and social pathways. A potential biological pathway exists in which mothers who consume more nutrients beginning earlier in gestation experience better health and their infants have better fetal growth and development than mothers who consume fewer nutrients or consume them later in gestation (9,33,38,55). As shown in animal studies, better maternal nutrition leads to better placental function and fetal development, even if fetal growth or size is not influenced (56).…”

Human Physiology

“…While the effects of maternal under-nutrition on fetal growth have been extensively studied (Lechtig et al 1975;Godfrey, 1998), little is known about the effects of materno-fetal oxygen deprivation. Previously, it was reported that high altitude, rather than maternal economic status, is associated with reduced mean birth weight and increased infant mortality in Bolivia (Giussani & Barker, 1999).…”