“…High-strength CAD-CAM ceramics include IPS e.max CAD ® (Ivoclar Vivadent, Schaan, Liechtenstein), composed of lithium disilicate (LDS), and VITA SUPRINITY ® (VITA Zahnfabrik, Bad Zäckingen, Germany) catalogued as zirconium-reinforced lithium silicate (ZRLS), composed of two crystalline phases (lithium metasilicate and zirconium dioxide) [12][13][14]. Hybrid materials can be classified as polymer-infiltrated ceramic networks (PICN), such as VITA ENAMIC ® (VITA Zahnfabrik, BadZäckingen, Germany), and resin nanoceramics (RNC), such as LAVA™ ULTIMATE (3M, St. Paul, Minn, USA) [15][16][17] ( Table 1) [18,19]. According to the literature, there is little consensus with regard to the biomechanical behavior of these new restoration materials.…”