Influence of local particle concentration gradient forces on the flow-mediated mass transport in a numerical model of magnetic drug targeting

Gonella, Veronica C.; Hanser, Friedrich; Vorwerk, Johannes; Odenbach, Stefan; Baumgarten, Daniel

doi:10.1016/j.jmmm.2020.167490

Cited by 6 publications

(3 citation statements)

References 40 publications

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“…Moreover, there have been recent biomedical advances in their use in hyperthermia treatment (Zhang, Gu & Wang 2007) and magnetic drug targeting, experimentally (Asfer, Saroj & Panigrahi 2017) and theoretically (Voltairas, Fotiadis & Michalis 2002; Gonella et al. 2020).…”

Section: Introductionmentioning

confidence: 99%

“…In industry, they are most commonly used for dynamic sealing and heat dissipation (Scherer & Figueiredo Neto 2005), and there has been investigation into their use in inkjet printing (Charles 1987;Abdel Fattah, Ghosh & Puri 2016) and three-dimensional printing (Löwa et al 2019), where the jet disintegrates into drops that are then directed by a magnetic field. Moreover, there have been recent biomedical advances in their use in hyperthermia treatment (Zhang, Gu & Wang 2007) and magnetic drug targeting, experimentally (Asfer, Saroj & Panigrahi 2017) and theoretically (Voltairas, Fotiadis & Michalis 2002;Gonella et al 2020).…”

Section: Introductionmentioning

confidence: 99%

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Linear stability of a ferrofluid centred around a current-carrying wire

Briggs

Mestel

2022

J. Fluid Mech.

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Investigated first is the linear stability of a Newtonian ferrofluid centred on a rigid wire, surrounded by another ferrofluid with a different magnetic susceptibility. An electric current runs through the wire, generating an azimuthal magnetic field that produces a magnetic stress at the interface of the fluids. Three-dimensional disturbances to the system are considered, and the linearised Navier–Stokes equations are solved analytically in terms of an implicit expression for the growth rate of the disturbance. The growth rate is found numerically for arbitrary Reynolds number, and given explicitly in the inviscid and Stokes regimes. Investigated next is a ferrofluid whose magnetic susceptibility varies radially, centred on a rigid wire, subject to a non-uniform azimuthal field. It is proven that if the gradient of the susceptibility is positive anywhere in the fluid, then the system is linearly unstable. Moreover, it is proven that applying an axial field can stabilise disturbances for both continuous and discontinuous susceptibilities.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Linear stability of a ferrofluid centred around a current-carrying wire

Briggs

Mestel

2022

J. Fluid Mech.

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“…Most common are their industrial applications for dynamic sealing and heat dissipation, for example, in audio speakers [4]. Bio-medical applications include magnetic drug targeting, where the FF allows for a localized treatment, and hyperthermia treatment in cancer therapy [5–8]. Theoretical analysis of FFs is, therefore, useful in determining the stability of various geometrical configurations and the possible parameter ranges for a chosen application.…”

Section: Introductionmentioning

confidence: 99%

Stability of an inhomogeneous ferrofluid in a channel, subject to a normal field

Briggs

Mestel

2022

Proc. R. Soc. A.

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The stability of a ferrofluid with a fairly arbitrary non-uniform magnetic susceptibility between two parallel walls, subject to a non-uniform magnetic field acting normal to the walls, is investigated. The susceptibility may depend on position and the field strength, and the stationary state is such that the gradient of the susceptibility with respect to the modulus of the field is negative. Previous work suggests that the configuration may be linearly unstable, as regions of higher susceptibility do not coincide with regions of strongest field, and this is proved here. Adding a constant field in the plane of the layer suppresses parallel instabilities, but has no effect on those orthogonal to it. However, it is demonstrated that stability can be achieved by applying a rapidly rotating field.

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Numerical Studies on Magnetic Driven Targeted Drug Delivery in Human Vasculature

Tamboli,

Murallidharan

2024

J Indian Inst Sci

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Influence of local particle concentration gradient forces on the flow-mediated mass transport in a numerical model of magnetic drug targeting

Cited by 6 publications

References 40 publications

Linear stability of a ferrofluid centred around a current-carrying wire

Linear stability of a ferrofluid centred around a current-carrying wire

Stability of an inhomogeneous ferrofluid in a channel, subject to a normal field

Numerical Studies on Magnetic Driven Targeted Drug Delivery in Human Vasculature

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