Influence of lead on the glutathione status of Atlantic croaker tissues

Thomas, P. John; Juedes, Marlene J.

doi:10.1016/0166-445x(92)90009-c

Cited by 37 publications

(7 citation statements)

References 48 publications

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“…Lead accumulation in the "viscera" sample includes uptake by intestine, kidney, and liver. Avid uptake of Pb ++ by these organs is consistent with observations of Thomas and Juedes (24) in a study with the saltwater fish Micropogonias undulates. The latter group found the greatest accumulation of 210 Pb in the intestine after administering radiolabeled lead nitrate in the diet along with unlabeled lead nitrate for prolonged periods (up to 6 weeks).…”

Section: Discussionsupporting

confidence: 89%

Tissue Lead Concentration during Chronic Exposure of Pimephales promelas (Fathead Minnow) to Lead Nitrate in Aquarium Water

Spokas

Spur

Smith

et al. 2006

Environ. Sci. Technol.

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The fathead minnow is a useful species for evaluating the toxicity of wastewater effluents. While this fish is widely used for "survival" studies of metal toxicity, little or no work has been done on the tissue distribution of metals in fathead minnows. To determine the distribution of tissue lead, aquarium studies were conducted for several weeks with fish maintained in soft synthetic freshwater. Lead- (II) nitrate was added to three aquaria attaining concentrations of 20-30 ppb (aquarium B), 100-140 ppb (aquarium C), and roughly 200 ppb (aquarium D). Results were compared to controls (aquarium A). During the initial week, the majority of aquarium D fish died, whereas few deaths occurred in the other groups. Lead accumulation was dose- and tissue-dependent, with highest uptake by the gills. Gill concentrations of aquarium D fish averaged about 4-fold higherthan in skeleton or skin and muscle. In vitro, lead (2.5-25 ppm) caused dose-dependent reductions in the ratio of reduced glutathione/oxidized glutathione (GSH/GSSG) in gills incubated in physiological buffer. These findings demonstrate that fathead minnow gills bind and accumulate waterborne lead rapidly and preferentially and raise the possibility that gill lipid peroxidation contributes to lead toxicity at low water hardness.

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Section: Discussionsupporting

confidence: 89%

Tissue Lead Concentration during Chronic Exposure of Pimephales promelas (Fathead Minnow) to Lead Nitrate in Aquarium Water

Spokas

Spur

Smith

et al. 2006

Environ. Sci. Technol.

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“…(Wilhelm Filho et al 2002) found that gill tissues are one of the main contributors of ROS generation in fish. This explanation is supported also by other studies by (Thomas and Wofford 1984; Gallagher et al 1992; Thomas and Juedes 1992) where they demonstrated higher level of GSH following exposing fish to stressor. (Oliveira et al 2008) showed a higher adaptive competence expressed as antioxidant defenses activation, namely GSH and glutathione peroxidase (GPX) in Liver against different concentration of Phenanthrene.…”

Section: Discussionsupporting

confidence: 82%

Protective role of adjuvant and potassium permanganate on oxidative stress response of Nile tilapia (Oreochromis niloticus) challenged with Saprolegnia ferax

Zahran

Risha

2013

SpringerPlus

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Saprolegniosis are one of the most important oomycetes affecting freshwater fish worldwide. It leads to huge losses in fish farms due to their massive destruction to the fish epidermis leading to sever heamodilution and death, yet little literature studied the oxidative stress response regarding the saprolegniosis. Nile tilapia fish were subcutaneously abraded and divided into four groups: control group, abraded but not challenged, infected group, challenged with Saprolegnia. ferax (S. ferax) zoospores 2 × 104 for one week, potassium permanganate (KMnO4) group, challenged with S. ferax zoospores 2 × 104 for one week then treated with KMnO4 and lasted for 2 weeks after, Freund’s complete adjuvant (FCA) group challenged with S. ferax zoospores 2 × 104 for one week then treated with FCA and lasted for 2 weeks after and control positive group, challenged with S. ferax zoospores 2 × 104 for 3 weeks. Higher mortalities were recovered from the challenged group, which declined upon treatment compared to the continued increased rate in the control positive group. Oxidative stress indicators Nitric Oxide (NO), glutathione (GSH) and superoxide dismutase (SOD) were measured; biochemical parameters: total protein, albumin, globulin, aspartate aminotranseferase (AST), and alanine aminoranferase (ALT) were also measured. Sodium (Na+) and potassium (K+) levels were measured as indicators of Plasma osmolality. Almost of the measured parameters showed varying reduction significant levels in treatment groups compared with the infected and the control ones. Thus, this study revealed that KMnO4 have a protective role against oxidative stress response, furthermore our data provide evidence for the role of FCA in modulating the oxidative stress response and enhancing fish immune response against infections.Electronic supplementary materialThe online version of this article (doi:10.1186/2193-1801-2-94) contains supplementary material, which is available to authorized users.

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“…Moreover, increase of GSH content may be related to prevention of oxidative challenge 34 . Aquatic organisms maintain high content of GSH in tissues and increased content has the function of protection that could provide the first line of defense against the influence of toxic heavy metals 35,36 . Esterases are considered as potential biomarkers to differentiate the levels of contaminants 37 .…”

Section: Resultsmentioning

confidence: 99%

Mercury Induced Biochemical Alterations As Oxidative Stress In Mugil Cephalus In Short Term Toxicity Test

Rajkumar¹,

Tennyson²

2013

Curr World Environ

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Mugil cephalus juveniles of size 2.5 ±0.6cm were exposed to mercury in short term chronic toxicity test through static renewal bioassay to detect the possible biochemical agent as biomarkers in aquatic pollution and in estuarine contamination as specific. Lipid peroxidation levels, glutathione S-transferase, catalase, reduced glutathione and acetylcholinesterase were studied as biochemical parameters.Increased thio-barbituric acid reactive substances levels were observed under exposure to mercury, leading to the oxidative damage resulting in lipid peroxidation. Decreased activities of antioxidants, catalase and increased glutathione-S-transferase under short term chronic exposures to mercury were more prominent in metal stress suggesting activation of physiological mechanism to scavenge the ROS produced. Decreased values of reduced glutathione on prolonged exposures to mercury indicate utilization of this antioxidant, either to scavenge oxy-radical or act in combination with other enzymes. The acetylcholinesterase activity was found to be decreased during mercury exposure. The results also suggest that mercury alters the active oxygen metabolism by modulating antioxidant enzyme activities, which can be used as biomarker to detect sub-lethal effects in aquatic pollution.

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Influence of lead on the glutathione status of Atlantic croaker tissues

Cited by 37 publications

References 48 publications

Tissue Lead Concentration during Chronic Exposure of Pimephales promelas (Fathead Minnow) to Lead Nitrate in Aquarium Water

Tissue Lead Concentration during Chronic Exposure of Pimephales promelas (Fathead Minnow) to Lead Nitrate in Aquarium Water

Protective role of adjuvant and potassium permanganate on oxidative stress response of Nile tilapia (Oreochromis niloticus) challenged with Saprolegnia ferax

Mercury Induced Biochemical Alterations As Oxidative Stress In Mugil Cephalus In Short Term Toxicity Test

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