Abstract:This study aimed to evaluate the influence of late N‐acetylcysteine (NAC) administration on cardiac remodeling in long‐term follow‐up postinfarction rats. Methods: Myocardial infarction (MI) was induced by left coronary occlusion. Four months later, rats were assigned to three groups: Sham (n=13), MI‐C (MI without treatment, n=16), and MI‐NAC (MI treated with N‐acetylcysteine, 120 mg/kg/day, n=16). Six months after surgery, cardiac structures and function were evaluated by transthoracic Doppler echocardiogram … Show more
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