Influence of Irrigation Sequence on the Adhesion of Root Canal Sealers to Dentin: A Fourier Transform Infrared Spectroscopy and Push-out Bond Strength Analysis

Epigallocatechin-3-gallate increased the push out bond strength of an epoxy resin sealer to root dentin

“…The theory has not been widely accepted because of the lack of evidence. However, recent study confirmed the bond between the epoxide ring and the collagen network using a fourier transform infrared spectroscopy analysis 13) . Thus, chemical irrigants should be used with consideration as it caused a change to the collagen network in dentin and affected the bond strength of an epoxy resin sealer.…”

“…The chemical irrigants could cause a change in chemical composition, dentin wettability and collagen degradation which potentially affected the sealing ability of the resin-typed sealer. The exposed collagen network should be preserved even when using an epoxy resin sealer 13) . In this present study, the final flush with EGCG resulted in collagen stabilization which increased the strength of the covalent bonds formed with the epoxide ring of an epoxy resin sealer.…”

“…Final irrigation with EDTA and NaOCl caused collagen degradation influencing the covalent bonds forming between an epoxy resin sealer and root dentin, thus decreasing the bond strength of an epoxy resin sealer to root dentin. It is advised to use only EDTA as a final flush when using an epoxy resin sealer to exposed the collagen fibrils in order to bind to the epoxide rings of an epoxy resin sealer 10,13) . However, collagen degradation in EDTA-treated dentin was observed over time interfering durability of resindentin bonds 14) .…”

Histologic Assessment of Debridement of the Root Canal Isthmus of Mandibular Molars by Irrigant Activation Techniques Ex Vivo

“…Although there appears to be no consensus on a ''recommended'' irrigation regimen, the most commonly clinically used regimen involves a final flush of NaOCl after NaOCl-EDTA irrigation. However, this protocol can result in destruction of the collagen that is normally encapsulated by hydroxyapatite (28). Furthermore, a final rinse of NaOCl has been shown to reduce the adhesion of epoxy resin-based root canal sealers (28), whereas remnant NaOCl or EDTA can negatively influence the hydration of tricalcium silicate-based materials (29).…”

Effect of sodium hypochlorite irrigation with or without surfactants on the bond strength of an epoxy-based sealer to dentin

“…AH Plus can bond chemically to the amino groups of dentinal collagen [22]. The collagen network needs to be exposed and more importantly be well preserved to ensure the quality of bonding process.…”