Influence of Irradiation on Capsules of Silicone Implants Covered with Acellular Dermal Matrix in Mice

Lee, Joon Seok; Lee, Jung Ho; Ryu, Jeong Yeop; Park, Shin‐Hyung; Park, Jiyoung; Han, Man‐Hoon; Lee, Jeeyeon; Park, Ho Yong; Yang, Jung Dug

doi:10.1007/s00266-021-02618-4

Cited by 4 publications

(8 citation statements)

References 36 publications

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“…The use of ADM in implant-based breast reconstruction following mastectomy has received a lot of attention recently (2,83,91,94,104,(107)(108)(109)(110)(111)(112). The advantages of ADM in implant-based breast surgery include implant stabilization, improved aesthetic outcomes, and reduced capsular contracture risks, donor site morbidity, and postoperative pain (34,83,86,109,(112)(113)(114).…”

Section: Breastmentioning

confidence: 99%

“…Despite their strength, their complications, like erosion into the bowel wall, adhesion, infection, and fistula formation, have limited their use in abdominal wall reconstruction ( 81 ). So, biological meshes such as ADM have recently gained attention ( 1 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 83 , 87 , 89 , 101 , 121 – 126 , 127 ). ADM is biocompatible, integrates into the surrounding tissue, and allows vascularization ( 1 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 83 , 87 , 89 , 101 , 121 – 126 , 127 ).…”

Section: Abdomenmentioning

confidence: 99%

“…So, biological meshes such as ADM have recently gained attention ( 1 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 83 , 87 , 89 , 101 , 121 – 126 , 127 ). ADM is biocompatible, integrates into the surrounding tissue, and allows vascularization ( 1 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 83 , 87 , 89 , 101 , 121 – 126 , 127 ). The revascularization of ADM by the host makes it resistant to infection ( 1 , 10 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 52 , 83 , 87 , 89 , 101 , 121 – 126 , 127 – 129 ).…”

Section: Abdomenmentioning

confidence: 99%

“…ADM is biocompatible, integrates into the surrounding tissue, and allows vascularization ( 1 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 83 , 87 , 89 , 101 , 121 – 126 , 127 ). The revascularization of ADM by the host makes it resistant to infection ( 1 , 10 , 16 , 21 , 29 , 33 , 34 , 38 , 45 , 52 , 83 , 87 , 89 , 101 , 121 – 126 , 127 – 129 ).…”

Section: Abdomenmentioning

confidence: 99%

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Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost

Mohammadyari

Parvin²,

Khorvash³

et al. 2023

Front. Transplant.

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Modern tissue engineering has made substantial advancements that have revolutionized plastic surgery. Acellular dermal matrix (ADM) is an example that has gained considerable attention recently. ADM can be made from humans, bovines, or porcine tissues. ADM acts as a scaffold that incorporates into the recipient tissue. It is gradually infiltrated by fibroblasts and vascularized. Fortunately, many techniques have been used to remove cellular and antigenic components from ADM to minimize immune system rejection. ADM is made of collagen, fibronectin, elastin, laminin, glycosaminoglycans, and hyaluronic acid. It is used in critical wounds (e.g., diabetic wounds) to protect soft tissue and accelerate wound healing. It is also used in implant-based breast reconstruction surgery to improve aesthetic outcomes and reduce capsule contracture risk. ADM has also gained attention in abdominal and chest wall defects. Some studies have shown that ADM is associated with less erosion and infection in abdominal hernias than synthetic meshes. However, its higher cost prevents it from being commonly used in hernia repair. Also, using ADM in tendon repair (e.g., Achilles tendon) has been associated with increased stability and reduced rejection rate. Despite its advantages, ADM might result in complications such as hematoma, seroma, necrosis, and infection. Moreover, ADM is expensive, making it an unsuitable option for many patients. Finally, the literature on ADM is insufficient, and more research on the results of ADM usage in surgeries is needed. This article aims to review the literature regarding the application, Benefits, and costs of ADM in reconstructive surgery.

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Section: Breastmentioning

confidence: 99%

Section: Abdomenmentioning

confidence: 99%

Section: Abdomenmentioning

confidence: 99%

Section: Abdomenmentioning

confidence: 99%

See 2 more Smart Citations

Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost

Mohammadyari

Parvin²,

Khorvash³

et al. 2023

Front. Transplant.

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show abstract

“…In addition, a considerable part of patients undergoing a mastectomy has previously undergone breast conserving treatment consisting of tumorectomy and adjuvant radiotherapy. However, IBBR in irradiated patients has become more feasible with the introduction of ADMs and the use of AFG to counteract radiation damage and complications such as capsular contracture or implant extrusion [ 59 , 79 , 80 , 84 ]. Interestingly, prepectoral implant placement has been shown to be beneficial in this context.…”

Section: Radiation Therapy and Prepectoral Ibbrmentioning

confidence: 99%

Implant-Based Breast Reconstruction after Mastectomy, from the Subpectoral to the Prepectoral Approach: An Evidence-Based Change of Mind?

Weinzierl

Schmauß

Brucato

et al. 2022

JCM

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Over the last years, prepectoral implant-based breast reconstruction has undergone a renaissance due to several technical advancements regarding mastectomy techniques and surgical approaches for the placement and soft tissue coverage of silicone implants. Initially abandoned due to the high incidence of complications, such as capsular contraction, implant extrusion, and poor aesthetic outcome, the effective prevention of these types of complications led to the prepectoral technique coming back in style for the ease of implant placement and the conservation of the pectoralis muscle function. Additional advantages such as a decrease of postoperative pain, animation deformity, and operative time contribute to the steady gain in popularity. This review aims to summarize the factors influencing the trend towards prepectoral implant-based breast reconstruction and to discuss the challenges and prospects related to this operative approach.

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Protective role of transforming growth factor-Β3 (TGF-Β3) in the formation of radiation-induced capsular contracture around a breast implant: In vivo experimental study

Sezer,

Ozalp,

Imge Ucar-Goker

et al. 2024

International Journal of Pharmaceutics

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Influence of Irradiation on Capsules of Silicone Implants Covered with Acellular Dermal Matrix in Mice

Cited by 4 publications

References 36 publications

Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost

Acellular dermal matrix in reconstructive surgery: Applications, benefits, and cost

Implant-Based Breast Reconstruction after Mastectomy, from the Subpectoral to the Prepectoral Approach: An Evidence-Based Change of Mind?

Protective role of transforming growth factor-Β3 (TGF-Β3) in the formation of radiation-induced capsular contracture around a breast implant: In vivo experimental study

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