INFLUENCE OF IODOALPHIONIC ACID (PRIODAX), WITH AND WITHOUT THYROTROPIN, ON THYROIDAL I<sup>131</sup>UPTAKE IN EUTHYROID PATIENTS*

Newman, Stanley; Cupp, Claude M.

doi:10.1210/jcem-17-1-94

Cited by 9 publications

(1 citation statement)

References 4 publications

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“…In addition, many groups recommend iodine depletion diets to optimize the therapeutic response to radioactive iodine in these patients [ 2 , 3 ]. Thus, avoidance of iodinated contrast material is particularly important as it can lessen the effectiveness of radioactive therapy [ 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Urinary Iodine Clearance following Iodinated Contrast Administration: A Comparison of Euthyroid and Postthyroidectomy Subjects

Tsang

Scoggan

et al. 2014

Journal of Thyroid Research

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Purpose. To compare iodine clearance following iodinated contrast administration in thyroidectomised thyroid cancer patients and euthyroid individuals. Methods. A convenience population (6 thyroidectomised thyroid cancer patients and 7 euthyroid controls) was drawn from patients referred for iodinated contrast-enhanced computed tomography (CT) studies. Subjects had sequential urine samples collected up to 6 months (50 samples from the thyroidectomised and 63 samples from the euthyroid groups). t-tests and generalised estimating equations (GEE) were used to test for group differences in urinary iodine creatinine ratios. Results. Groups had similar urinary iodine creatinine ratios at baseline, with a large increase 2 weeks following iodinated contrast (P = 0.005). Both groups had a return of urinary iodine creatinine ratios to baseline by 4 weeks, with no significant group differences overall or at any time point. Conclusions. Thyroidectomised patients did not have a significantly different urinary iodine clearance than euthyroid individuals following administration of iodinated contrast. Both had a return of urinary iodine creatinine ratios to baseline within 4 weeks.

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