Influence of infant-feeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa: a prospective cohort study

Coutsoudis, Anna; Pillay, Kubendran; Spooner, Elizabeth; Kuhn, Louise; Coovadia, Hoosen M.

doi:10.1016/s0140-6736(99)01101-0

Cited by 457 publications

(252 citation statements)

References 20 publications

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“…1 Breastfeeding is an important route of acquisition of HIV infection for infants, in the absence of antiretroviral prophylaxis. 1 However, mixed feeding rather than EBF, is associated with an increased HIV transmission risk 11 . HIV-positive mothers find it difficult to independently make decisions on infant feeding and are uncertain about the safety of breastfeeding 12 .…”

Section: Maternal Medical Conditionsmentioning

confidence: 99%

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Comparison of infant-feeding practices in two health subdistricts with different baby-friendly status in Mpumalanga province

MNutrition

Statistician²

2015

South African Journal of Clinical Nutrition

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Section: Maternal Medical Conditionsmentioning

confidence: 99%

“…11 Although exclusive breastfeeding is effectively promoted in the sub-district with accredited facilities, it seems that mothers were not advised on the dangers associated with mixed feeding and supported to practise exclusive breastfeeding for the first 6 months of life.…”

Section: Mixed Feedingmentioning

confidence: 99%

Comparison of infant-feeding practices in two health subdistricts with different baby-friendly status in Mpumalanga province

MNutrition

Statistician²

2015

South African Journal of Clinical Nutrition

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“…The percentage increase in the rate of use of supplements in breastfeeding mothers was greatest between 10 and 12 weeks for water, phala and other solids. This frequent use of early mixed feeding has been shown to increase the risk of mother to child HIV transmission in breastfeeding mothers (Coutsoudis et al, 1999). Although the mechanism to explain this is unclear, the possibility must be considered that contaminated fluids and foods introduced in babies receiving early mixed feeding damage the bowel and facilitate entry into the tissues of HIV in breast milk.…”

Section: Mean W/a Z-scorementioning

confidence: 99%

Breast and complementary feeding practices in relation to morbidity and growth in Malawian infants

2005

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Objectives: The objective of this study was to compare growth, morbidity incidence and risk factors for undernutrition between infants receiving complementary feeding early, before 3 months of age, with those receiving complementary foods after 3 months in a poor rural Malawian community. Methods: A cohort of babies was enrolled at birth for follow-up to 12 months of age. Weight, length, morbidity and feeding patterns were recorded at 4 weekly intervals from birth to 52 weeks. Results: Mean age at introduction of water was 2.5 months (range 0-11.8), complementary foods 3.4 months (range, 1.0-10.7) and solids 4.5 months (range 1.2-13.8). Over 40% of infants had received complementary foods by 2 months and 65% by 3 months. The proportion of exclusively breast-fed infants, which included those receiving supplemental water, was 13% at 4 months, 6.3% at 5 months and 1.5% at 6 months. Infants with early complementary feeding had lower weight for age at 3 and 6 months (Po0.05), and at 9 months (P ¼ 0.07) and at 2 months they were approximately 200 g lighter. Early complementary feeding was significantly associated with increased risk for respiratory infection (Po0.05), and marginally increased risk for eye infection and episodes of malaria. Maternal illiteracy was associated with early complementary feeding (OR ¼ 2.1, 95% CI 1.3, 3.2), while later complementary feeding was associated with reduced infant morbidity and improved growth. Conclusion: Breast-feeding promotion programmes should target illiterate women. Greater emphasis is required to improve complementary feeding practices.

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“…A partial solution to this problem was suggested by the preliminary observation that exclusive breastfeeding conferred less risk of breast milk transmission than mixed feeding [2,3]. This has led to calls for early cessation of exclusive breastfeeding to provide the young infant some of the healthful immune and nutritive benefits of breast milk while minimizing the duration of exposure to HIV [3,4].…”

Section: Introductionmentioning

confidence: 99%

Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume

Thea

Aldrovandi

Kankasa

et al. 2006

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Influence of infant-feeding patterns on early mother-to-child transmission of HIV-1 in Durban, South Africa: a prospective cohort study

Cited by 457 publications

References 20 publications

Comparison of infant-feeding practices in two health subdistricts with different baby-friendly status in Mpumalanga province

Comparison of infant-feeding practices in two health subdistricts with different baby-friendly status in Mpumalanga province

Breast and complementary feeding practices in relation to morbidity and growth in Malawian infants

Post-weaning breast milk HIV-1 viral load, blood prolactin levels and breast milk volume

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