Influence of Hydrophilic Co-Monomer on the Drug Release from Hydrogels with Thermosensitive N-(isopropyl)acrylamide Derivatives

Semi-Crystalline Copolymer Hydrogels as Smart Drug Carriers: In Vitro Thermo-Responsive Naproxen Release Study

“…[30]. The influence of the formulation based on N-isopropylacrylamide and hydroxypropyl methylcellulose thermosensitive hydrogel for the naproxen sodium release was investigated [31][32][33][34]. Release tests showed that modification of the cross-linker type influenced the properties of synthesized polymeric particles obtained via surfactant free precipitation polymerization [32].…”

DNA response element-based smart drug delivery systems for precise drug release

“…Compared to other materials ( e.g. , polymers, 28 liposomes, 29 and micelles 30 ) for controllable drug delivery, DNA response element-based nanosystems possess several distinctive advantages. First, it is facile to assemble DNA nanosystem-based carriers with predictable physical and chemical properties using different assembly methods ( e.g.…”

“…[25][26][27] Such a feature provides a great possibility for controllable drug release on demand at specific sites, thereby enhancing therapeutic efficacy and minimizing biotoxicity. Compared to other materials (e.g., polymers, 28 liposomes, 29 and micelles 30 ) for controllable drug delivery, DNA response element-based nanosystems possess several distinctive advantages. First, it is facile to assemble DNA nanosystem-based carriers with predictable physical and chemical properties using different assembly methods (e.g., tile-mediated assembly, dynamic assembly, hybrid assembly, and DNA origami), 31,32 which provide much flexibility to achieve desired custom functions.…”

Evaluation of the potential of nanoparticles containing active substances in selected chronic diseases

“…Currently, modern controlled drug release systems are being extensively studied. 2 However, one of the important issues in the process of developing new drugs is the bioavailability of active pharmaceutical ingredient (API). To overcome this potential problem, several methods can be used, including micro-and nanonization, which can help reduce a substance to a micro-or nanosize without changing its chemical properties.…”