2016
DOI: 10.1007/s10517-016-3155-2
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Influence of High Blood Pressure on Microcirculation in Cerebral Cortex of Young Rats

Abstract: We studied the density and structure of the microvascular network of the pia mater, the blood flow rate and oxygen saturation in the sensorimotor cortex of young spontaneously hypertensive rats (SHR). The density of the microvascular network in hypertensive animals was by ~1.4 times lower than in normotensive Wistar-Kyoto rats (control) and arteriolar bed density was lower by ~1.9 times. The blood flow rate in tissue and oxygen saturation in the sensorimotor cortex in SHR rats were significantly lower than in … Show more

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Cited by 8 publications
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“…However, from immature laboratory animals only hamsters were not studied for cell proliferation, immunomorphological alteration in the structural components of the spleen at different time of postnatal ontogenesis [11,12]. These aspects are the most relevant, as the spleen takes an active part in ensuring the immunological response of the body, iron recycling in t red blood cell dissolution, proliferation of immune competent cells in T -and B-dependent areas of the body that determine the immune status and health of developing animals [13][14][15].…”
Section: Introductionmentioning
confidence: 99%
“…However, from immature laboratory animals only hamsters were not studied for cell proliferation, immunomorphological alteration in the structural components of the spleen at different time of postnatal ontogenesis [11,12]. These aspects are the most relevant, as the spleen takes an active part in ensuring the immunological response of the body, iron recycling in t red blood cell dissolution, proliferation of immune competent cells in T -and B-dependent areas of the body that determine the immune status and health of developing animals [13][14][15].…”
Section: Introductionmentioning
confidence: 99%