Influence of Haptic Materials on the Adherence of Staphylococci to Intraocular Lenses

Incidence and outcomes evaluation of endophthalmitis management after phacoemulsification and 3-piece silicone intraocular lens implantation over 6 years in a single eye unit

“…Increased adherence of staphylococci to polypropylene material in comparison with PMMA material has been suggested. 17 It has also been demonstrated by Griffiths et al 18 of Staphylococcus epidermidis to the IOL in vitro confers a greater resistance to antibiotics. Some experimental data and clinical studies suggest an increased adherence of bacteria to silicone IOLs, although others do not corroborate this finding.…”

Comparison of the adherence of E.Coli and S. Aureus to ten different prosthetic mesh grafts: In vitro experimental study

“…The difference seen in our study may result from in vitro circumstances. The ability of S. aureus to form a biofilm, sialic acid-forming slime, bacterial enzymes increasing adhesion, the molecular properties of the bacteria, and the graft all play important roles in adhesion [14,18,29], but we do not know which effects are greater in vitro or in vivo.…”

In vitro influence of vancomycin on adhesion of a Staphylococcus epidermidis strain encoding intercellular adhesion locus ica to intraocular lenses

“…8,[15][16][17][18] Polypropylene was the first biomaterial for which this relation of cause and effect was proven. 8,19,20 Thus, one might potentially decrease endophthalmitis incidence and clinical pathogenicity by reducing the adhesion of bacteria to intraocular implants, especially that of the most frequently involved germ, S epidermidis. 18 Clinical findings on the prevention of endophthalmitis led to the current practice of adding filtered antibiotics (vancomycin 20 mg/mL and/or gentamicin 8 mg/mL) to the infusion bottle during cataract surgery, a practice popularized by J.P. Gills, MD, based on his surgical observations of more than 50 000 cases.…”