Influence of gamma-irradiation sterilization and temperature on the fracture toughness of ultra-high-molecular-weight polyethylene

Pascaud, R. S.; Evans, W. T.; McCullagh, P.J.; FitzPatrick, D.

doi:10.1016/s0142-9612(96)00207-4

Cited by 46 publications

(21 citation statements)

References 28 publications

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“…g-irradiation has been widely used in the sterilization of numerous biomaterials and milk [146][147][148][149][150]. Appropriate doses of irradiation are effective against several bacteria, viruses and fungi; however, it has been found to affect the biological properties and tissue integrity [151,152].…”

Section: Lyophilization and G-irradiation Sterilizationmentioning

confidence: 99%

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

et al. 2010

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Section: Lyophilization and G-irradiation Sterilizationmentioning

confidence: 99%

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

et al. 2010

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“…2,3 It is likely that oxidation caused by gamma irradiation accelerates the fatigue process of UHMWPE. 13,14,15 Correspondence to: N. Tomita, Institute for Frontier Medical Sciences, Kyoto University, 53 Kawahara-cho Shogoin Sakyo-ku, Kyoto 606, Japan (e-mail: ntomita@frontier.kyoto-u.ac.jp) Bell et al reported that the cracks propagated through the subsurface oxidized band. Our data observing sliding fatigue tested specimen also demonstrated that the subsurface cracks propagated along grain boundaries.…”

Section: Introductionmentioning

confidence: 99%

Prevention of fatigue cracks in ultrahigh molecular weight polyethylene joint components by the addition of vitamin E

Tomita

Kitakura

Onmori

et al. 1999

J. Biomed. Mater. Res.

120

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Flaking-type wear, so-called delamination, is often observed in polyethylene joint components. This is thought to occur partly due to crack formation and propagation at grain boundaries. This study examined the effect of vitamin E on the crack formation and/or propagation in UHMWPE by using 2-dimensional sliding fatigue testing and micro indenter testing. An in vitro sliding fatigue test was performed under two simplified articulating movements, and the cracks produced were observed by scanning acoustic tomography (SAT). Gamma-irradiated ultrahigh molecular weight polyethylene (UHMWPE) specimens demonstrated a smaller area of accumulated cracks as compared to virgin specimens, when the loading movement was reciprocated on a single linear locus. However, four out of five gamma-irradiated UHMWPE specimens exhibited severe flaking-like destruction under the complicated sliding condition, suggesting that gamma irradiation accelerated crack propagation under multidirectional loading. All the gamma-irradiated vitamin-E-containing specimens demonstrated no subsurface crack formation and no flaking-like destruction. Results using micro indenter testing showed that the dynamic hardness at grain boundary was higher than that in grain, and was increased by gamma irradiation. This hardening at grain boundary was reduced by adding vitamin E. It is possible that the presence of vitamin E prevents crack propagation partly due to reduced hardness at grain boundaries. The gamma-irradiated vitamin-E-containing UHMWPE is a promising material to prevent flaking-like destruction of polyethylene joint components.

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“…Using equation 1 and 2, the normalized load, P n is defined as (3) The functional forms of the deformation function, H(v pl /W) that are commonly used are the power law [18] and the LMN function [19]. where β and n are the coefficient and exponent in the power law function and where L, M, and N are three constants in the LMN function.…”

Section: Single Specimen Normalization Methodsmentioning

confidence: 99%

“…As such, the articulating surface is subject to damage and wear and, under certain conditions, the components may also be at risk of fracture [1]. Therefore, there has been much interest in the evaluation of fracture resistance of different UHMWPE formulations under static and cyclic loading conditions [2][3][4][5][6].…”

Section: Introductionmentioning

confidence: 99%

Static fracture resistance of ultra high molecular weight polyethylene using the single specimen normalization method

2008

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Fracture of Ultra High Molecular Weight Polyethylene (UHMWPE) components used in total joint replacements is a clinical concern. UHMWPE materials exhibits stable crack growth under static loading, therefore, their fracture resistance is generally characterized using the J-R curve. The multiple specimen method recommended by ASTM for evaluation of the J-R curve for polymers is time and material intensive. In this study, the applicability of a single specimen method based on load normalization to predict J-R curves of UHMWPE materials is evaluated. The normalization method involves determination of a deformation function. In this study, the J-R curves obtained using a power law based deformation function and the LMN curve based deformation function were compared. The results support the use of the power law based deformation function when using the single specimen approach to predict J-R curves for UHMWPE materials.

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Influence of gamma-irradiation sterilization and temperature on the fracture toughness of ultra-high-molecular-weight polyethylene

Cited by 46 publications

References 28 publications

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

Preservation, sterilization and de-epithelialization of human amniotic membrane for use in ocular surface reconstruction

Prevention of fatigue cracks in ultrahigh molecular weight polyethylene joint components by the addition of vitamin E

Static fracture resistance of ultra high molecular weight polyethylene using the single specimen normalization method

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