Influence of flavonoid-rich fruit and vegetable intake on diabetic retinopathy and diabetes-related biomarkers

Mahoney, Sara E.; Loprinzi, Paul D.

doi:10.1016/j.jdiacomp.2014.06.011

Cited by 60 publications

(43 citation statements)

References 31 publications

(44 reference statements)

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“…A single-blind, dose-dependent, parallel randomized controlled dietary intervention of men and women who were low consumers of fruits and vegetables also reported reductions in CRP levels (P = .001) in the group that had at least 4 portions/d of highflavonoid fruit and vegetable consumption [58]. Similar findings have been reported in other observational [59] and clinical studies [60]. At least one other study did not see the same inverse association with markers of inflammation [61]; however, this randomized controlled trial was conducted in a specialized population (overweight and obese men) and used anthocyanins extracted from purple carrots rather than cranberries.…”

Section: Discussionsupporting

confidence: 79%

Adult consumers of cranberry juice cocktail have lower C-reactive protein levels compared with nonconsumers

Duffey

Sutherland

2015

Nutrition Research

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Section: Discussionsupporting

confidence: 79%

Adult consumers of cranberry juice cocktail have lower C-reactive protein levels compared with nonconsumers

Duffey

Sutherland

2015

Nutrition Research

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“…For instance, many vegetables, fruits, and seeds, such as cereals and legumes, contain minerals, polyphenols, and other phytochemicals that combat oxidative stress, inflammation, and insulin resistance (32,33). In fact, high consumption of flavonoid-rich fruits and vegetables (7,8) has been associated to a lower risk of diabetic retinopathy.…”

Section: Discussionmentioning

confidence: 99%

“…The etiology of type 2 diabetes complications is poorly understood. Diet is one of the lifestyle factors that may play an important role in preventing and managing these conditions (3,4), particularly diabetic retinopathy and nephropathy (5)(6)(7)(8)(9)(10). However, few studies have explored the relationship between dietary habits and diabetes complications.…”

mentioning

confidence: 99%

“…However, few studies have explored the relationship between dietary habits and diabetes complications. Most studies have examined the associations between individual foods or food groups and nutrients and diabetes complications (7,8,(11)(12)(13)(14)(15)(16)(17) instead of focusing on dietary patterns, which is the most sensible approach to test the role of the overall diet on nutrition-related diseases.…”

mentioning

confidence: 99%

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Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial

et al. 2015

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OBJECTIVETo date no clinical trials have evaluated the role of dietary patterns on the incidence of microvascular diabetes complications. We hypothesized that a nutritional intervention based on the Mediterranean diet (MedDiet) would have greater protective effect on diabetic retinopathy and nephropathy than a lowfat control diet. RESEARCH DESIGN AND METHODSThis was a post hoc analysis of a cohort of patients with type 2 diabetes participating in the PREvención con DIeta MEDiterránea (PREDIMED) study, a multicenter randomized nutritional intervention trial conducted in a population at high cardiovascular risk. Individuals with type 2 diabetes who were free of microvascular complications at enrollment (n = 3,614, aged 55-80 years) were randomly assigned to one of three dietary interventions: MedDiet supplemented with extravirgin olive oil (MedDiet+EVOO), MedDiet supplemented with mixed nuts (MedDiet+Nuts), or a low-fat control diet. Two independent outcomes were considered: new onset of diabetic retinopathy and nephropathy. Hazard ratios (HRs) were calculated using multivariable-adjusted Cox regression. RESULTSDuring a median follow-up of 6.0 years, we identified 74 new cases of retinopathy and 168 of nephropathy. Compared with the control diet, multivariable-adjusted HRs for diabetic retinopathy were 0.56 (95% CI 0.32-0.97) for the ) for the MedDiet+Nuts. No between-group differences were found for nephropathy. When the yearly updated information on adherence to the MedDiet was considered, the HR for retinopathy in the highest versus the lowest quintile was 0.34 (0.13-0.89; P = 0.001 for trend). No significant associations were found for nephropathy. CONCLUSIONSA MedDiet enriched with EVOO may protect against diabetic retinopathy but not diabetic nephropathy.

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“…Flavonoid, a large category of plant polyphenol secondary metabolites and biologically active non-nutrients, is one kind of antioxidants and widely distributed in herbs, fruits, vegetables, etc. 1 Numerous studies suggest that estrogen-like isoflavonoids present in soy foods promote cardiovascular, skeletal, and postmenopausal health. 2 Anthocyanidins from fruits have strong antioxidant protection towards lipid peroxidation.…”

Section: Introductionmentioning

confidence: 99%

Optimization, Bio accessibility of Tricin and Anti-oxidative Activity of Extract from Black Bamboo Leaves

Shang¹,

Hyun²,

Lee³

et al. 2016

FRA

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Introduction: Bamboo and black bamboo leaves have long been used as folk remedies for the treatment of hypertension, cardiovascular disease in oriental regions. Many studies have shown that bamboo leaves extract and its main phenolic compounds have antioxidant activity before bio accessibility assessment. Methods: The optimized extraction methods for biological compound tricin by pressuriz ed liquid extraction (PLE) from black bamboo leaves were studied and tricin abundant black bamboo extracts were obtained. Subsequently, the digestive stability, bio accessibility and anti-oxidative activity (total phenolics, DPPH, ABTS) of tricin and tricin abundant extract were examined by in vitro simulated digestion system. Results: The optimized extraction methods for biological compound tricin by pressurized liquid extraction (PLE) from black bamboo leaves were obtained at 200

show abstract

Influence of flavonoid-rich fruit and vegetable intake on diabetic retinopathy and diabetes-related biomarkers

Cited by 60 publications

References 31 publications

Adult consumers of cranberry juice cocktail have lower C-reactive protein levels compared with nonconsumers

Adult consumers of cranberry juice cocktail have lower C-reactive protein levels compared with nonconsumers

Mediterranean Diet, Retinopathy, Nephropathy, and Microvascular Diabetes Complications: A Post Hoc Analysis of a Randomized Trial

Optimization, Bio accessibility of Tricin and Anti-oxidative Activity of Extract from Black Bamboo Leaves

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