Influence of Eyelid Pressure on Fluorescein Staining of Ocular Surface in Dry Eyes

Yoshioka, Eriko; Yamaguchi, Masahiko; Shiraishi, Atsushi; Kono, Tomoko; Ohta, Kiyohiko; Ohashi, Yuichi

doi:10.1016/j.ajo.2015.06.028

Cited by 19 publications

(28 citation statements)

References 32 publications

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“…In dry eye, the cold nociceptors are sensitive to a change of 0.1 degrees celsius . Alternatively, the lens may prevent frictional contact between the lid and the cornea during the blink, which can also stimulate nociceptors . Lastly, microscopic epithelial defects may heal faster due to the bandage effect…”

Section: Discussionmentioning

confidence: 99%

Effects of wearing a daily disposable lens on tear film: a randomised controlled trial

Chong

Yeo

Too

et al. 2016

Clinical and Experimental Optometry

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Section: Discussionmentioning

confidence: 99%

Effects of wearing a daily disposable lens on tear film: a randomised controlled trial

Chong

Yeo

Too

et al. 2016

Clinical and Experimental Optometry

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“…The skull conformation in Chihuahuas varies widely, and this might result in the variability of the ulcer types. It could be surmised that the difference in palpebral fissure width and skull conformation in these dogs may have some effects on the ocular surface health in these dogs via alterations in blink rate, ocular surface friction, 32,33 composition of tears or minute pathological changed in the cornea. In non-BC breeds, the Toy poodle was the third most common breed and tended to be frequently affected by Grade 1 UK.…”

Section: Discussionmentioning

confidence: 99%

Breed prevalence of canine ulcerative keratitis according to depth of corneal involvement

Iwashita

Wakaiki

Kazama

et al. 2020

Veterinary Ophthalmology

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Objective To investigate the breed prevalence of canine ulcerative keratitis (UK) according to the depth of corneal involvement. Procedures Dogs diagnosed with ulcerative keratitis from 2008 to 2017 at the Triangle Animal Eye Clinic were included in this study. Only breeds with more than 20 eyes affected were selected. UK lesions were classified as superficial (Grade 1), stromal (Grade 2) or descemetoceles and perforations (Grade 3) and compared between brachycephalic (BC) and non‐BC dog breeds. Results Of 8877 dogs evaluated at Triangle Animal Eye Clinic from 2008 to 2017, 1109 eyes of 1018 dogs (male, 326 eyes; neutered male, 253 eyes; female, 211 eyes; spayed female, 316 eyes; and unknown sex, 3 eyes) aged between 0.1 and 19.2 years (mean ± standard deviation [SD], 8.33 ± 4.24 years) were diagnosed with UK. The number of eyes that was classified as Grade 1 was 359 eyes (187 non‐BC and 172 BC), Grade 2 was 373 eyes (60 non‐BC and 313 BC) and Grade 3 was 377 eyes (47 non‐BC and 330 BC). Significant differences were observed between BC and non‐BC dogs for all grades of UK. BC dogs were significantly more frequently affected by Grades 2 and 3 and less frequently by Grade 1 UK (P < .01). French bulldogs are more likely to be affected with Grade 1. Conclusions Brachycephalic dogs are more likely to have deeper corneal involvement in UK. This study provides novel data on the prevalence of superficial UK, which was low in BC dogs and high in non‐BC breeds.

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“…The eyelid pressure was measured for all subjects using a commercially developed measurement system with tactile pressure sensors (DigiTacts Single Point Sensors; Pressure Profile Systems, Inc, Los Angeles, California, USA) [ 10 ]. The lower eyelid pressure was measured by a single ophthalmologist for all subjects.…”

Section: Methodsmentioning

confidence: 99%

“…Recently, a commercially developed device with tactile pressure sensors, known as a blepharo-tensiometer, was introduced to evaluate the tension exerted by the eyelids [ 8 ]. The blepharo-tensiometer has been used to investigate the mechanical friction between the eyelids and the ocular surface, particularly in patients with dry eye and lid-wiper epitheliopathy [ 9 , 10 ]. The sensor measures the compression pressure between the eyelid and conjunctiva during eyelid closure.…”

Section: Introductionmentioning

confidence: 99%

Estimation of Eyelid Pressure Using a Blepharo-Tensiometer in Patients with Functional Nasolacrimal Duct Obstruction

Lee

Choi

Lee

2018

Journal of Ophthalmology

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Purpose To compare the eyelid pressure between patients with functional nasolacrimal duct obstruction (FNLDO) and normal controls using blepharo-tensiometer, and to evaluate the relationship between eyelid pressure and the outcomes of silicone intubation (SI) in patients with FNLDO. Study design Prospective case-control study. Methods We enrolled 36 eyes of 36 patients with suspected FNLDO who underwent SI and 36 healthy eyes of age-matched controls. One eye of each patient with FNLDO was randomly selected for analysis. The eyelid pressure was estimated using a blepharo-tensiometer and compared between the control and FNLDO groups. The relationship between eyelid pressure and clinical variables was analyzed. The outcomes of SI were assessed at 6 months after surgery using subjective and objective criteria. Results The eyelid pressure was significantly lower in the FNLDO group than in the control group (P=0.008). In the control group, the eyelid pressure was correlated with age (P<0.001) and lower eyelid laxity (P=0.016). In the FNLDO group, the eyelid pressure was only correlated with age (P<0.001). The success rate of SI for FNLDO was 69.4% (25 of 36 eyes). The eyelid pressure was higher in the surgical success subgroup than in the failure subgroup, although the difference was not statistically significant (P=0.08). Conclusions Our results suggest that the eyelid pressure measured using a blepharo-tensiometer has a diagnostic value since it is decreased in patients with FNLDO. The role of eyelid pressure as a possible predictor of the outcomes of SI for FNLDO should be investigated in further studies. This trial is registered with KCT0002828.

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Influence of Eyelid Pressure on Fluorescein Staining of Ocular Surface in Dry Eyes

Cited by 19 publications

References 32 publications

Effects of wearing a daily disposable lens on tear film: a randomised controlled trial

Effects of wearing a daily disposable lens on tear film: a randomised controlled trial

Breed prevalence of canine ulcerative keratitis according to depth of corneal involvement

Estimation of Eyelid Pressure Using a Blepharo-Tensiometer in Patients with Functional Nasolacrimal Duct Obstruction

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